Gut microbiota is involved in many physiological functions and its imbalance is associated with several diseases, particularly with inflammatory bowel diseases. Mucosa-associated microbiota could have a key role in induction of host immunity and in inflammatory process. Although the role of fungi has been suggested in inflammatory disease pathogenesis, the fungal microbiota has not yet been deeply explored. Here we analysed the bacterial and fungal composition of the mucosa-associated microbiota of Crohn's disease patients and healthy subjects.
Fungal Dysbiosis in Mucosa-associated Microbiota of Crohn's Disease Patients / Liguori, Giuseppina; Lamas, Bruno; Richard, Mathias L; Brandi, Giovanni; da Costa, Gregory; Hoffmann, Thomas W; Di Simone, Massimo Pierluigi; Calabrese, Carlo; Poggioli, Gilberto; Langella, Philippe; Campieri, Massimo; Sokol, Harry. - In: JOURNAL OF CROHN'S AND COLITIS. - ISSN 1873-9946. - STAMPA. - 12:(2015), pp. 1-10. [10.1093/ecco-jcc/jjv209]
Fungal Dysbiosis in Mucosa-associated Microbiota of Crohn's Disease Patients
LIGUORI, GIUSEPPINA;BRANDI, GIOVANNI;DI SIMONE, MASSIMO PIERLUIGI;CALABRESE, CARLO;POGGIOLI, GILBERTO;CAMPIERI, MASSIMO;
2015
Abstract
Gut microbiota is involved in many physiological functions and its imbalance is associated with several diseases, particularly with inflammatory bowel diseases. Mucosa-associated microbiota could have a key role in induction of host immunity and in inflammatory process. Although the role of fungi has been suggested in inflammatory disease pathogenesis, the fungal microbiota has not yet been deeply explored. Here we analysed the bacterial and fungal composition of the mucosa-associated microbiota of Crohn's disease patients and healthy subjects.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
