Using a previously developed in vitro model to characterize the enterocyte-adherent microbiota fraction, we explored the potential of the probiotic strain Bifidobacterium animalis ssp. lactis BI07 to modulate the inflammation-dependent dysbioses of the enterocyte-adherent microbiota from 12 healthy human donors. According to our findings, B. animalis ssp. lactis BI07 is effective in limiting the increase of pro-inflammatory pathobionts on the inflamed mucosal site, supporting the recovery of a mutualistic community.
Bifidobacterium animalis ssp. lactis BI07 modulates the tumor necrosis factor alpha-dependent imbalances of the enterocyte-associated intestinal microbiota fraction / Centanni, Manuela; Turroni, Silvia; Rampelli, Simone; Biagi, Elena; Quercia, Sara; Consolandi, Clarissa; Severgnini, Marco; Brigidi, Patrizia; Candela, Marco. - In: FEMS MICROBIOLOGY LETTERS. - ISSN 0378-1097. - ELETTRONICO. - 357:2(2014), pp. 157-163. [10.1111/1574-6968.12515]
Bifidobacterium animalis ssp. lactis BI07 modulates the tumor necrosis factor alpha-dependent imbalances of the enterocyte-associated intestinal microbiota fraction
CENTANNI, MANUELA;TURRONI, SILVIA;RAMPELLI, SIMONE;BIAGI, ELENA;QUERCIA, SARA;BRIGIDI, PATRIZIA;CANDELA, MARCO
2014
Abstract
Using a previously developed in vitro model to characterize the enterocyte-adherent microbiota fraction, we explored the potential of the probiotic strain Bifidobacterium animalis ssp. lactis BI07 to modulate the inflammation-dependent dysbioses of the enterocyte-adherent microbiota from 12 healthy human donors. According to our findings, B. animalis ssp. lactis BI07 is effective in limiting the increase of pro-inflammatory pathobionts on the inflamed mucosal site, supporting the recovery of a mutualistic community.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.