Oral squamous cell carcinoma (OSCC) is commonly preceded by oral potentially malignant lesions (OPML). The aim of the present study was to assess, by bisulfite next-generation sequencing (NGS), the methylation status of a list of candidate genes obtained from oral brushings to early detect OPML and OSCC.
DNA methylation analysis by bisulfite next-generation sequencing for early detection of oral squamous cell carcinoma and high-grade squamous intraepithelial lesion from oral brushing / Morandi, Luca; Gissi, Davide; Tarsitano, Achille; Asioli, Sofia; Monti, Valentina; Del Corso, Giacomo; Marchetti, Claudio; Montebugnoli, Lucio; Foschini, Maria Pia. - In: JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY. - ISSN 1010-5182. - ELETTRONICO. - 1:(2015), pp. 1-1. [10.1016/j.jcms.2015.07.028]
DNA methylation analysis by bisulfite next-generation sequencing for early detection of oral squamous cell carcinoma and high-grade squamous intraepithelial lesion from oral brushing
MORANDI, LUCA;GISSI, DAVIDE BARTOLOMEO;TARSITANO, ACHILLE;ASIOLI, SOFIA;DEL CORSO, GIACOMO;MARCHETTI, CLAUDIO;MONTEBUGNOLI, LUCIO;FOSCHINI, MARIA PIA
2015
Abstract
Oral squamous cell carcinoma (OSCC) is commonly preceded by oral potentially malignant lesions (OPML). The aim of the present study was to assess, by bisulfite next-generation sequencing (NGS), the methylation status of a list of candidate genes obtained from oral brushings to early detect OPML and OSCC.| File | Dimensione | Formato | |
|---|---|---|---|
|
morandi_am.pdf
accesso aperto
Tipo:
Postprint
Licenza:
Licenza per Accesso Aperto. Creative Commons Attribuzione - Non commerciale - Non opere derivate (CCBYNCND)
Dimensione
1.05 MB
Formato
Adobe PDF
|
1.05 MB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
