NPM1 mutations have been reported to be the most frequent mutations in acute myeloid leukemia (AML). They are associated with a wide spectrum of morphologic subtypes of AML, normal karyotype and FLT3 mutations. The high frequency of NPM1 mutations might provide a suitable marker for monitoring residual disease of AML.
NPM1 mutations are more stable than FLT3 mutations during the course of disease in patients with acute myeloid leukemia / Palmisano M; Grafone T; Ottaviani E; Testoni N; Baccarani M; Martinelli G.. - In: HAEMATOLOGICA. - ISSN 0390-6078. - STAMPA. - 92(9)::(2007), pp. 1268-1269. [10.3324/haematol.11202]
NPM1 mutations are more stable than FLT3 mutations during the course of disease in patients with acute myeloid leukemia.
GRAFONE, TIZIANA;OTTAVIANI, EMANUELA;TESTONI, NICOLETTA;BACCARANI, MICHELE;MARTINELLI, GIOVANNI
2007
Abstract
NPM1 mutations have been reported to be the most frequent mutations in acute myeloid leukemia (AML). They are associated with a wide spectrum of morphologic subtypes of AML, normal karyotype and FLT3 mutations. The high frequency of NPM1 mutations might provide a suitable marker for monitoring residual disease of AML.File in questo prodotto:
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