Chiroptical spectroscopies, optical rotatory dispersion (ORD) and circular dichroism (CD) [1], were developed in the 1960s to study mainly steroidal ketones [2] and octahedral metal complexes [3]. Subsequently, several different chromophores were investigated by CD using different theoretical analyses [4]; the exciton approach, in particular, has been very successful for studying molecular systems containing two or more absorbing chromophores, for example, biaryls [4, 5] and proteins [6]. At the present time, the outstanding sensitivity of CD is employed mainly to study biological macromolecules and their perturbations by external factors. In the field of supramolecular chemistry, CD has several interesting applications. In particular, assembly processes leading to the formation of helical superstructures can be investigated [7]. In those cases where gels are formed by chiral monomers through self-assembly processes, it seems natural to use CD to monitor the progress of the process and, hopefully, to obtain information on the assembled structures that complements that from other techniques (see Chapters 10-12).
Circular dichroism for studying gel-like phases
SPADA, GIAN PIERO;
2006
Abstract
Chiroptical spectroscopies, optical rotatory dispersion (ORD) and circular dichroism (CD) [1], were developed in the 1960s to study mainly steroidal ketones [2] and octahedral metal complexes [3]. Subsequently, several different chromophores were investigated by CD using different theoretical analyses [4]; the exciton approach, in particular, has been very successful for studying molecular systems containing two or more absorbing chromophores, for example, biaryls [4, 5] and proteins [6]. At the present time, the outstanding sensitivity of CD is employed mainly to study biological macromolecules and their perturbations by external factors. In the field of supramolecular chemistry, CD has several interesting applications. In particular, assembly processes leading to the formation of helical superstructures can be investigated [7]. In those cases where gels are formed by chiral monomers through self-assembly processes, it seems natural to use CD to monitor the progress of the process and, hopefully, to obtain information on the assembled structures that complements that from other techniques (see Chapters 10-12).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
