The present paper describes the production, using a microfluidic approach, of microparticles (constituted of cellulose acetate) and O/ W emulsions (constituted of PEG-6 corn oil droplets). The general production strategy is based on the formation of water-in-oil multiphase flow by a focusing mechanism (X-junction chip). The innovative aspect of the work is represented by the fabrication procedure for the microfluidic chip production. The chips were designed and fabricated by a low cost approach using a shrinkable biocompatible polymer.
PRODUCTION OF LOW COST MICROFLUIDIC CHIPS BY A “SHRINKING” APPROACH: APPLICATIONS TO EMULSION AND MICROPARTICLE PRODUCTION / L. CAPRETTO; S. FOCAROLI; X.L. ZHANG; S. MAZZITELLI; C. NASTRUZZI. - In: JOURNAL OF CONTROLLED RELEASE. - ISSN 0168-3659. - STAMPA. - 148:(2010), pp. e26-e28. [10.1016/j.jconrel.2010.07.038]
PRODUCTION OF LOW COST MICROFLUIDIC CHIPS BY A “SHRINKING” APPROACH: APPLICATIONS TO EMULSION AND MICROPARTICLE PRODUCTION
FOCAROLI, STEFANO;
2010
Abstract
The present paper describes the production, using a microfluidic approach, of microparticles (constituted of cellulose acetate) and O/ W emulsions (constituted of PEG-6 corn oil droplets). The general production strategy is based on the formation of water-in-oil multiphase flow by a focusing mechanism (X-junction chip). The innovative aspect of the work is represented by the fabrication procedure for the microfluidic chip production. The chips were designed and fabricated by a low cost approach using a shrinkable biocompatible polymer.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
