Different substituted ferrocene–guanine conjugates were prepared, and their electrochemical behavior was investigated. A new approach for the introduction of ferrocene in guanine’s 9-position through a quite effective SN1-type reaction was disclosed. The electrochemical behavior of the various derivatives can be used as standard for the quantification and analysis of DNA strands.
New Approaches toward Ferrocene–Guanine Conjugates: Synthesis and Electrochemical Behavior / Matteo Iurlo; Luca Mengozzi ; Stefania Rapino ; Massimo Marcaccio ; Rosaria C. Perone ; Stefano Masiero; Piergiorgio Cozzi; Francesco Paolucci. - In: ORGANOMETALLICS. - ISSN 0276-7333. - STAMPA. - 33:18(2014), pp. 4986-4993. [10.1021/om5002809]
New Approaches toward Ferrocene–Guanine Conjugates: Synthesis and Electrochemical Behavior
IURLO, MATTEO;MENGOZZI, LUCA;RAPINO, STEFANIA;MARCACCIO, MASSIMO;PERONE, ROSARIA CARMELA;MASIERO, STEFANO;COZZI, PIER GIORGIO;PAOLUCCI, FRANCESCO
2014
Abstract
Different substituted ferrocene–guanine conjugates were prepared, and their electrochemical behavior was investigated. A new approach for the introduction of ferrocene in guanine’s 9-position through a quite effective SN1-type reaction was disclosed. The electrochemical behavior of the various derivatives can be used as standard for the quantification and analysis of DNA strands.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
