In canine (D) and human, but not guinea pig (GP), ventricular myocytes, a spike-and-dome profile (SaD), supported by Ito, characterizes ventricular repolarization. β-adrenergic stimulation (by isoprenaline, ISO) shortens action potential (AP) duration (APD) in D (and human) myocytes, but prolongs it in GP ones. © 2013 CCAL.
Effects of species-dependent differences in action potential shape in setting β-adrenergic-stimulation induced current / L. Sala;B. Hegyi;C. Bartolucci;C. Altomare;M. Rocchetti;G. Mostacciuolo;S. Severi;N. Szentandrassy;P. Nanasi;A. Zaza. - In: COMPUTING IN CARDIOLOGY. - ISSN 2325-8861. - ELETTRONICO. - 40:(2013), pp. 381-384.
Effects of species-dependent differences in action potential shape in setting β-adrenergic-stimulation induced current
BARTOLUCCI, CHIARA;SEVERI, STEFANO;
2013
Abstract
In canine (D) and human, but not guinea pig (GP), ventricular myocytes, a spike-and-dome profile (SaD), supported by Ito, characterizes ventricular repolarization. β-adrenergic stimulation (by isoprenaline, ISO) shortens action potential (AP) duration (APD) in D (and human) myocytes, but prolongs it in GP ones. © 2013 CCAL.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
