Chiral non-racemic perazamacrocyles containing three or more nitrogen atoms in the form of different functions (amine, amide, imine) are prepared from optically active amines, diamines, -aminoacids, and their derivatives, by properly selected methodologies. The many applications of these optically pure perazamacrocycles rely on the basic and/or hydrogen bond donor properties of the nitrogen functions and include metal ions coordination, supramolecular chemistry, material science, molecular and enantioselective recognition, and asymmetric catalysis. Part 1 describes the preparation of polyamino, poly(amino-amido), polyamido macrocycles by procedures involving mainly nucleophilic substitution and acylation reactions, but also ring closing metathesis, multicomponent and click reactions in the cyclization step.
Chiral Perazamacrocycles: Synthesis and Applications. Part 1
SAVOIA, DIEGO;GUALANDI, ANDREA
2013
Abstract
Chiral non-racemic perazamacrocyles containing three or more nitrogen atoms in the form of different functions (amine, amide, imine) are prepared from optically active amines, diamines, -aminoacids, and their derivatives, by properly selected methodologies. The many applications of these optically pure perazamacrocycles rely on the basic and/or hydrogen bond donor properties of the nitrogen functions and include metal ions coordination, supramolecular chemistry, material science, molecular and enantioselective recognition, and asymmetric catalysis. Part 1 describes the preparation of polyamino, poly(amino-amido), polyamido macrocycles by procedures involving mainly nucleophilic substitution and acylation reactions, but also ring closing metathesis, multicomponent and click reactions in the cyclization step.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
