An Efficient Simulator for Boolean Network Models

Boolean networks (BNs), first introduced by Kauffman as genetic regulatory network models, are the subject of notable works in complex systems biology literature. BN models lately garnered much attention because it has been shown that BNs can capture important phenomena in genetics and biology in general. In this work, we illustrate the main properties and design principles of a new efficient, flexible and extensible BN simulator, named the Boolean Network Toolkit. This simulator makes it possible to easily set up experiments and analyse the most relevant features of BN’s dynamics.