The effect of the film-forming solution pH on the triple-helix content, thermal stability, and mechanical properties of gelatin films was investigated. The films were prepared from solutions at different pHs of type A pigskin gelatin, and the mechanical characteristics were determined. At pHs higher than 9 and lower than 5, Young’s modulus, E, and the stress at break, σb, of the films decreased significantly. Cross-linking with genipin reduced deformation at break, εb, and increased Young’s modulus. The intensity of the 1.1-nm X-ray diffraction reflection and the denaturation enthalpy decreased at these pHs, indicating that the triple helix reduced. Preliminary in vitro tests on the cross-linked samples indicated good cell proliferation and viability.
Role of pH on stability and mechanical properties of gelatin films. Journal of Bioactive and Compatible Polymers / M. Gioffrè; P. Torricelli; S. Panzavolta; K. Rubini; A. Bigi.. - In: JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS. - ISSN 0883-9115. - STAMPA. - 27:(2012), pp. 57-67. [10.1177/0883911511431484]
Role of pH on stability and mechanical properties of gelatin films. Journal of Bioactive and Compatible Polymers.
PANZAVOLTA, SILVIA;RUBINI, KATIA;BIGI, ADRIANA
2012
Abstract
The effect of the film-forming solution pH on the triple-helix content, thermal stability, and mechanical properties of gelatin films was investigated. The films were prepared from solutions at different pHs of type A pigskin gelatin, and the mechanical characteristics were determined. At pHs higher than 9 and lower than 5, Young’s modulus, E, and the stress at break, σb, of the films decreased significantly. Cross-linking with genipin reduced deformation at break, εb, and increased Young’s modulus. The intensity of the 1.1-nm X-ray diffraction reflection and the denaturation enthalpy decreased at these pHs, indicating that the triple helix reduced. Preliminary in vitro tests on the cross-linked samples indicated good cell proliferation and viability.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.