Hearing loss and chronic kidney disease (CKD) are frequently associated; in addition to possible dysfunctions of genetic origin, clinical studies about the frequent incidence of hearing disorders in patients with CKD were reported. We aimed to find out a satisfactory explanation for the mechanisms underlying this association. We present a review of the literature, particularly dealing with the association of hearing loss with haemodialysis and CKD of non-familial origin. The recorded studies seem to indicate that a link between labyrinthine and kidney disorders is reliably supposed to exist, but a clear explanation is lacking. A possible explanation, that hemodynamic changes could play a role, is proposed. As a clear statement is lacking, we suggest that a functional interaction based on the consequences of a hemodynamic imbalance can play a role and substantiate a reliable explanation for the frequent association of non-syndromic CKD and hearing loss.

Kidney disease and inner ear sufferance of non-familial origin: a review of the literature and a proposal of explanation

PIRODDA, ANTONIO;FERRI, GIAN GAETANO;RAIMONDI, MARIA CHIARA;BORGHI, CLAUDIO
2012

Abstract

Hearing loss and chronic kidney disease (CKD) are frequently associated; in addition to possible dysfunctions of genetic origin, clinical studies about the frequent incidence of hearing disorders in patients with CKD were reported. We aimed to find out a satisfactory explanation for the mechanisms underlying this association. We present a review of the literature, particularly dealing with the association of hearing loss with haemodialysis and CKD of non-familial origin. The recorded studies seem to indicate that a link between labyrinthine and kidney disorders is reliably supposed to exist, but a clear explanation is lacking. A possible explanation, that hemodynamic changes could play a role, is proposed. As a clear statement is lacking, we suggest that a functional interaction based on the consequences of a hemodynamic imbalance can play a role and substantiate a reliable explanation for the frequent association of non-syndromic CKD and hearing loss.
2012
Pirodda A; Ferri GG; Raimondi MC; Borghi C.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/111584
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