PERINI, GIOVANNI
PERINI, GIOVANNI
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Docenti di ruolo di Ia fascia
A critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies.
2012 Gronbaek K.; Muller-Tidow C.; Perini G.; Lehmann S.; Bach Treppendahl M.; Mills K.; Plass C.; Schlegelberger B.
A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma
2021 Gamble L.D.; Purgato S.; Henderson M.J.; Di Giacomo S.; Russell A.J.; Pigini P.; Murray J.; Valli E.; Milazzo G.; Giorgi F.M.; Cowley M.; Ashton L.J.; Bhalshankar J.; Schleiermacher G.; Rihani A.; Van Maerken T.; Vandesompele J.; Speleman F.; Versteeg R.; Koster J.; Eggert A.; Noguera R.; Stallings R.L.; Tonini G.P.; Fong K.; Vaksman Z.; Diskin S.J.; Maris J.M.; London W.B.; Marshall G.M.; Ziegler D.S.; Hogarty M.D.; Perini G.; Norris M.D.; Haber M.
A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma
2012 Giovanni Perini; Emanuele Valli; Samuele Gherardi; Simone Di Giacomo; Giorgio Milazzo; Timothy R. Wagenaar; Michael R. Green
A new BCR-ABL1 Drosophila model as a powerful tool to elucidate pathogenesis and progression of chronic myeloid leukemia
2019 Roberto Bernardoni, Giorgia Giordani, Elisabetta Signorino, Sara Monticelli, Francesca Messa, Monica Pradotto, Valentina Rosso, Enrico Bracco, Angela Giangrande, Giovanni Perini, Giuseppe Saglio, Daniela Cilloni
A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF
2011 Iraci N.; Diolaiti D.; Papa A.; Porro A.; Valli E.; Gherardi S.; Herold S.; Eilers M.; Bernardoni R.; Della Valle G.; Perini G.
ABCC multidrug transporters in childhood neuroblastoma: influence on tumor biology and clinical outcome, independent of cytotoxic drug efflux
2011 Henderson M.; Porro A.; Munoz M.; Iraci N.; Xue C.; Murray J.; Flemming C.; Smith J.; Fletcher J.; Gherardi S.; Kwek K.; Russel A.; London W.; Buxton A.; Ashton L.; Sartorelli A.; Cohn S.; Schwab M.; Marshall G; Perini G.; Norris M.
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis
2007 Liu T; Tee AE; Porro A; Smith SA; Dwarte T; Liu PY; Iraci N; Sekyere E; Haber M; Norris MD; Diolaiti D; Della Valle G; Perini G; Marshall GM.
Altered gene silencing and human diseases.
2006 Perini G; Tupler R.
Analisi Genetica Avanzata
2012 Bernardoni R.; Perini G.
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
2011 Trazzi S.; Mitrugno V.M.; Valli E.; Fuchs C.; Rizzi S.; Guidi S.; Perini G.; Bartesaghi R.; Ciani E.
ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112
2011 I Iacobucci; F Cattina; S Pomella; A Lonetti; A Ferrari; C Papayannidis; S Trino; D Erriquez; V Guadagnuolo; E Ottaviani; S Formica; S Soverini; F Paoloni; M Vignetti; D Russo; G Perini; M Baccarani; G Martinelli
Association between genotypes and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the TOPS trial.
2010 ANGELINI S.; S. POVERINI; E. TURRINI; G. PERINI; F. PANE; F. QUARANTELLI; T. HUGHES; D. WHITE; D.W. KIM; H. GOH; J. RADICH; L. BEPPU; G. SAGLIO; D. CILLONI; C. TERRAGNA; I. IACOBUCCI; P. HRELIA; G. CANTELLI FORTI; T. KALEBIC; M. THORNQUIST; M. BACCARANI; G. MARTINELLI
Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy
2013 Angelini S; Soverini S; Ravegnini G; Barnett M; Turrini E; Thornquist M; Pane F; Hughes TP; White DL; Radich J; Kim DW; Saglio G; Cilloni D; Iacobucci I; Perini G; Woodman R; Cantelli-Forti G; Baccarani M; Hrelia P; Martinelli G
Association between transporters genotype and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the tops trial.
2009 ANGELINI S.; SOVERINI S.; TURRINI E.; PERINI G.; PANE F.; QUARANTELLI F.; HUGHES T.; WHITE D.; KIM D.W.; GOH H.; RADICH J.; BEPPU L.; SAGLIO G.; CILLONI D.; TERRAGNA C.; IACOBUCCI I.; HRELIA P.; CANTELLI FORTI G.; KALEBIC T.; THORNQUIST M.; BACCARANI M.; MARTINELLI G.
c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in Chronic Myelogenous Leukemia CD34+ hematopoietic progenitor cells
2011 A. Porro; N. Iraci; S. Soverini; D. Diolaiti; S. Gherardi; C. Terragna; S. Durante; E. Valli; T. Kalebic; R. Bernardoni; C. Perrod; M. Haber; M.D. Norris; M. Baccarani; G. Martinelli; G. Perini
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells
2012 VALLI E; TRAZZI S; FUCHS C; ERRIQUEZ D; BARTESAGHI R; PERINI G; CIANI E
CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains
2004 Politi, V; Perini, G; Trazzi, S; Pliss, A; Raska, I; Earnshaw, Wc; Della Valle, G
Centromere sliding on a mammalian chromosome
2015 Purgato, Stefania; Belloni, Elisa; Piras, Francesca M.; Zoli, Monica; Badiale, Claudia; Cerutti, Federico; Mazzagatti, Alice; Perini, Giovanni; Della Valle, Giuliano; Nergadze, Solomon G.; Sullivan, Kevin F.; Raimondi, Elena; Rocchi, Mariano; Giulotto, Elena
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming
2021 Tao L.; Moreno-Smith M.; Ibarra-Garcia-Padilla R.; Milazzo G.; Drolet N.A.; Hernandez B.E.; Oh Y.S.; Patel I.; Kim J.J.; Zorman B.; Patel T.; Kamal A.H.M.; Zhao Y.; Hicks J.; Vasudevan S.A.; Putluri N.; Coarfa C.; Sumazin P.; Perini G.; Parchem R.J.; Uribe R.A.; Barbieri E.
Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells
2010 Porro A.; Haber M.; Diolaiti D.; Iraci N.; Henderson M.; Gherardi S.; Valli E.; Munoz M.A.; Xue C.; Flemming C.; Schwab M.; Wong J.H.; Marshall G.M.; Della Valle G.; Norris M.D.; Perini G.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| A critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies. | Gronbaek K.; Muller-Tidow C.; Perini G.; Lehmann S.; Bach Treppendahl M.; Mills K.; Plass C.; Sch...legelberger B. | 2012-01-01 | HAEMATOLOGICA | - | 1.01 Articolo in rivista | - |
| A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma | Gamble L.D.; Purgato S.; Henderson M.J.; Di Giacomo S.; Russell A.J.; Pigini P.; Murray J.; Valli... E.; Milazzo G.; Giorgi F.M.; Cowley M.; Ashton L.J.; Bhalshankar J.; Schleiermacher G.; Rihani A.; Van Maerken T.; Vandesompele J.; Speleman F.; Versteeg R.; Koster J.; Eggert A.; Noguera R.; Stallings R.L.; Tonini G.P.; Fong K.; Vaksman Z.; Diskin S.J.; Maris J.M.; London W.B.; Marshall G.M.; Ziegler D.S.; Hogarty M.D.; Perini G.; Norris M.D.; Haber M. | 2021-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-13-01807-v2.pdf |
| A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma | Giovanni Perini; Emanuele Valli; Samuele Gherardi; Simone Di Giacomo; Giorgio Milazzo; Timothy R.... Wagenaar; Michael R. Green | 2012-01-01 | - | - | 4.03 Poster | - |
| A new BCR-ABL1 Drosophila model as a powerful tool to elucidate pathogenesis and progression of chronic myeloid leukemia | Roberto Bernardoni, Giorgia Giordani, Elisabetta Signorino, Sara Monticelli, Francesca Messa, Mon...ica Pradotto, Valentina Rosso, Enrico Bracco, Angela Giangrande, Giovanni Perini, Giuseppe Saglio, Daniela Cilloni | 2019-01-01 | HAEMATOLOGICA | - | 1.01 Articolo in rivista | Bernardoni et al, 2019.pdf |
| A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF | Iraci N.; Diolaiti D.; Papa A.; Porro A.; Valli E.; Gherardi S.; Herold S.; Eilers M.; Bernardoni... R.; Della Valle G.; Perini G. | 2011-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| ABCC multidrug transporters in childhood neuroblastoma: influence on tumor biology and clinical outcome, independent of cytotoxic drug efflux | Henderson M.; Porro A.; Munoz M.; Iraci N.; Xue C.; Murray J.; Flemming C.; Smith J.; Fletcher J....; Gherardi S.; Kwek K.; Russel A.; London W.; Buxton A.; Ashton L.; Sartorelli A.; Cohn S.; Schwab M.; Marshall G; Perini G.; Norris M. | 2011-01-01 | JOURNAL OF THE NATIONAL CANCER INSTITUTE | - | 1.01 Articolo in rivista | - |
| Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis | Liu T; Tee AE; Porro A; Smith SA; Dwarte T; Liu PY; Iraci N; Sekyere E; Haber M; Norris MD; Diola...iti D; Della Valle G; Perini G; Marshall GM. | 2007-01-01 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | - | 1.01 Articolo in rivista | - |
| Altered gene silencing and human diseases. | Perini G; Tupler R. | 2006-01-01 | CLINICAL GENETICS | - | 1.01 Articolo in rivista | - |
| Analisi Genetica Avanzata | Bernardoni R.; Perini G. | 2012-01-01 | - | McGraw-Hill | 5.01 Libro (Traduzione) | - |
| APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome. | Trazzi S.; Mitrugno V.M.; Valli E.; Fuchs C.; Rizzi S.; Guidi S.; Perini G.; Bartesaghi R.; Ciani E. | 2011-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112 | I Iacobucci; F Cattina; S Pomella; A Lonetti; A Ferrari; C Papayannidis; S Trino; D Erriquez; V G...uadagnuolo; E Ottaviani; S Formica; S Soverini; F Paoloni; M Vignetti; D Russo; G Perini; M Baccarani; G Martinelli | 2011-01-01 | BLOOD | - | 4.02 Riassunto (Abstract) | - |
| Association between genotypes and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the TOPS trial. | ANGELINI S.; S. POVERINI; E. TURRINI; G. PERINI; F. PANE; F. QUARANTELLI; T. HUGHES; D. WHITE; D....W. KIM; H. GOH; J. RADICH; L. BEPPU; G. SAGLIO; D. CILLONI; C. TERRAGNA; I. IACOBUCCI; P. HRELIA; G. CANTELLI FORTI; T. KALEBIC; M. THORNQUIST; M. BACCARANI; G. MARTINELLI | 2010-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy | Angelini S; Soverini S; Ravegnini G; Barnett M; Turrini E; Thornquist M; Pane F; Hughes TP; White... DL; Radich J; Kim DW; Saglio G; Cilloni D; Iacobucci I; Perini G; Woodman R; Cantelli-Forti G; Baccarani M; Hrelia P; Martinelli G | 2013-01-01 | HAEMATOLOGICA | - | 1.01 Articolo in rivista | 26°Haematol 98(2) 2013-1°Nome.pdf |
| Association between transporters genotype and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the tops trial. | ANGELINI S.; SOVERINI S.; TURRINI E.; PERINI G.; PANE F.; QUARANTELLI F.; HUGHES T.; WHITE D.; KI...M D.W.; GOH H.; RADICH J.; BEPPU L.; SAGLIO G.; CILLONI D.; TERRAGNA C.; IACOBUCCI I.; HRELIA P.; CANTELLI FORTI G.; KALEBIC T.; THORNQUIST M.; BACCARANI M.; MARTINELLI G. | 2009-01-01 | - | Società Italiana di Tossicologia | 4.02 Riassunto (Abstract) | - |
| c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in Chronic Myelogenous Leukemia CD34+ hematopoietic progenitor cells | A. Porro; N. Iraci; S. Soverini; D. Diolaiti; S. Gherardi; C. Terragna; S. Durante; E. Valli; T. ...Kalebic; R. Bernardoni; C. Perrod; M. Haber; M.D. Norris; M. Baccarani; G. Martinelli; G. Perini | 2011-01-01 | MOLECULAR CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells | VALLI E; TRAZZI S; FUCHS C; ERRIQUEZ D; BARTESAGHI R; PERINI G; CIANI E | 2012-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS | - | 1.01 Articolo in rivista | - |
| CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains | Politi, V; Perini, G; Trazzi, S; Pliss, A; Raska, I; Earnshaw, Wc; Della Valle, G | 2004-01-01 | JOURNAL OF CELL SCIENCE | - | 1.01 Articolo in rivista | - |
| Centromere sliding on a mammalian chromosome | Purgato, Stefania; Belloni, Elisa; Piras, Francesca M.; Zoli, Monica; Badiale, Claudia; Cerutti, ...Federico; Mazzagatti, Alice; Perini, Giovanni; Della Valle, Giuliano; Nergadze, Solomon G.; Sullivan, Kevin F.; Raimondi, Elena; Rocchi, Mariano; Giulotto, Elena | 2015-01-01 | CHROMOSOMA | - | 1.01 Articolo in rivista | - |
| CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming | Tao L.; Moreno-Smith M.; Ibarra-Garcia-Padilla R.; Milazzo G.; Drolet N.A.; Hernandez B.E.; Oh Y....S.; Patel I.; Kim J.J.; Zorman B.; Patel T.; Kamal A.H.M.; Zhao Y.; Hicks J.; Vasudevan S.A.; Putluri N.; Coarfa C.; Sumazin P.; Perini G.; Parchem R.J.; Uribe R.A.; Barbieri E. | 2021-01-01 | ADVANCED SCIENCE | - | 1.01 Articolo in rivista | Tao L et al.pdf |
| Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells | Porro A.; Haber M.; Diolaiti D.; Iraci N.; Henderson M.; Gherardi S.; Valli E.; Munoz M.A.; Xue C....; Flemming C.; Schwab M.; Wong J.H.; Marshall G.M.; Della Valle G.; Norris M.D.; Perini G. | 2010-01-01 | THE JOURNAL OF BIOLOGICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |