SALVESTRINI, VALENTINA
SALVESTRINI, VALENTINA
DIPARTIMENTO DI MEDICINA SPECIALISTICA, DIAGNOSTICA E SPERIMENTALE (attivo dal 28/10/2011 al 31/12/2022)
Acute myeloid leukemia cells constitutively express the immunoregulatory enzyme indoleamine 2,3-dioxygenase.
2007 Curti A; Aluigi M; Pandolfi S; Ferri E; Isidori A; Salvestrini V; Durelli I; Horenstein AL; Fiore F; Massaia M; Piccioli M; Pileri SA; Zavatto E; D'Addio A; Baccarani M; Lemoli RM.
ATP release from chemotherapy-treated dying leukemia cells Elicits an immune suppressive effect by increasing regulatory T cells and Tolerogenic dendritic cells
2017 Lecciso, Mariangela; Ocadlikova, Darina; Sangaletti, Sabina; Trabanelli, Sara; De Marchi, Elena; Orioli, Elisa; Pegoraro, Anna; Portararo, Paola; Jandus, Camilla; Bontadini, Andrea; Redavid, Annarita; Salvestrini, Valentina; Romero, Pedro; Colombo, Mario P.; Di Virgilio, Francesco; Cavo, Michele; Adinolfi, Elena; Curti, Antonio
CD103 marks a subset of human CD34+-derived langerin+ dendritic cells that induce T-regulatory cells via indoleamine 2,3-dioxygenase-1
2015 Ocadlikova, Darina; Trabanelli, Sara; Salvestrini, Valentina; Ciciarello, Marilena; Evangelisti, Cecilia; Lecciso, MARIANGELA STEFANIA; Sabattini, Elena; Righi, Simona; Piccioli, Milena; Pileri, Stefano; Lemoli, ROBERTO MASSIMO; Curti, Antonio
Corrigendum: Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells (Front. Oncol, (2020), 10, (1225), 10.3389/fonc.2020.01225)
2021 Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.; De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A.
Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells
2020 Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.; De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A.
Deregulated expression of miR-29a-3p, miR-494-3p and miR-660-5p affects sensitivity to tyrosine kinase inhibitors in CML leukemic stem cells
2017 Salati, Simona; Salvestrini, Valentina; Carretta, Chiara; Genovese, Elena; Rontauroli, Sebastiano; Zini, Roberta; Rossi, Chiara; Ruberti, Samantha; Bianchi, Elisa; Barbieri, Greta; Curti, Antonio; Castagnetti, Fausto; Gugliotta, Gabriele; Rosti, Gianantonio; Bergamaschi, Micaela; Tafuri, Agostino; Tagliafico, Enrico
Differential proteomic profile of leukemic CD34+ progenitor cells from chronic myeloid leukemia patients
2018 Ricciardi, Maria Rosaria; Salvestrini, Valentina; Licchetta, Roberto; Mirabilii, Simone; Forcato, Mattia; Gugliotta, Gabriele; Salati, Simona; Castagnetti, Fausto; Rosti, Gianantonio; Breccia, Massimo; Alimena, Giuliana; Manfredini, Rossella; Bicciato, Silvio; Lemoli, Roberto Massimo; Tafuri, Agostino*
Extracellular ATP exerts opposite effects on activated and regulatory CD4 + T cells via purinergic P2 receptor activation
2012 Trabanelli S; Ocadlíková D;Gulinelli S;Curti A;Salvestrini V; de Paula Vieira R;Idzko M;Di Virgilio F; Ferrari D;Lemoli R.M.
Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells
2017 Salvestrini, Valentina; Orecchioni, Stefania; Talarico, Giovanna; Reggiani, Francesca; Mazzetti, Cristina; Bertolini, Francesco; Orioli, Elisa; Adinolfi, Elena; Di Virgilio, Francesco; Pezzi, Annalisa; Cavo, Michele; Lemoli, Roberto M.; Curti, Antonio
Extracellular purines promote the differentiation of human bone marrow-derived mesenchymal stem cells to the osteogenic and adipogenic lineages.
2013 Ciciarello M; Zini R; Rossi L; Salvestrini V; Ferrari D; Manfredini R; Lemoli RM.
IL-18 and VEGF-A trigger type 2 innate lymphoid cell accumulation and pro-tumoral function in chronic myeloid leukemia
2023 Fiordi, Benedetta; Salvestrini, Valentina; Gugliotta, Gabriele; Castagnetti, Fausto; Curti, Antonio; Speiser, Daniel E.; Marcenaro, Emanuela; Jandus, Camilla; Trabanelli, Sara
Immunosenescence and immunotherapy in elderly acute myeloid leukemia patients: Time for a biology-driven approach
2018 Isidori, Alessandro*; Loscocco, Federica; Ciciarello, Marilena; Corradi, Giulia; Lecciso, Mariangela; Ocadlikova, Darina; Parisi, Sarah; Salvestrini, Valentina; Amadori, Sergio; Visani, Giuseppe; Curti, Antonio
Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells.
2010 Curti A; Trabanelli S; Onofri C; Aluigi M; Salvestrini V; Ocadlikova D; Evangelisti C; Rutella S; De Cristofaro R; Ottaviani E; Baccarani M; Lemoli RM.
Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells.
2007 Curti A; Pandolfi S; Valzasina B; Aluigi M; Isidori A; Ferri E; Salvestrini V; Bonanno G; Rutella S; Durelli I; Horenstein AL; Fiore F; Massaia M; Colombo MP; Baccarani M; Lemoli RM.
Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34- cell population with intrinsic resistance to imatinib.
2009 Lemoli RM; Salvestrini V; Bianchi E; Bertolini F; Fogli M; Amabile M; Tafuri A; Salati S; Zini R; Testoni N; Rabascio C; Rossi L; Martin-Padura I; Castagnetti F; Marighetti P; Martinelli G; Baccarani M; Ferrari S; Manfredini R.
Obesity may accelerate the aging process
2019 Salvestrini V.; Sell C.; Lorenzini A.
PGE2-induced IDO1 inhibits the capacity of fully mature DCs to elicit an in vitro antileukemic immune response
2015 Trabanelli, Sara; Lecciso, Mariangela; Salvestrini, Valentina; Cavo, Michele; Očadlíková, Darina; Lemoli, Roberto M; Curti, Antonio
Phospholipase C beta1 (PI-PLCbeta1)/Cyclin D3/protein kinase C (PKC) alpha signaling modulation during iron-induced oxidative stress in myelodysplastic syndromes (MDS)
2020 Alessandra Cappellini, Sara Mongiorgi, Carlo Finelli, Antonietta Fazio, Stefano Ratti, Maria Vittoria Marvi, Antonio Curti, Valentina Salvestrini, Andrea Pellagatti, Anna Maria Billi, Pann-Ghill Suh, James A. McCubrey, Jacqueline Boultwood, Lucia Manzoli, Lucio Cocco, Matilde Y. Follo
Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice.
2012 Salvestrini V.; Zini R.; Rossi L.; Gulinelli S.; Manfredini R.; Bianchi E.; Piacibello W.; Caione L.; Migliardi G.; Ricciardi M.R.; Tafuri A.; Romano M.; Salati S.; Di Virgilio F.; Ferrari S.; Baccarani M.; Ferrari D.; Lemoli R.M.
Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines.
2011 Ferrari D; Gulinelli S; Salvestrini V; Lucchetti G; Zini R; Manfredini R; Caione L; Piacibello W; Ciciarello M; Rossi L; Idzko M; Ferrari S; Di Virgilio F; Lemoli R.M.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Acute myeloid leukemia cells constitutively express the immunoregulatory enzyme indoleamine 2,3-dioxygenase. |
Curti A; Aluigi M; Pandolfi S; Ferri E; Isidori A; Salvestrini V; Durelli I; Horenstein AL; Fior...e F; Massaia M; Piccioli M; Pileri SA; Zavatto E; D'Addio A; Baccarani M; Lemoli RM. |
2007-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| ATP release from chemotherapy-treated dying leukemia cells Elicits an immune suppressive effect by increasing regulatory T cells and Tolerogenic dendritic cells | Lecciso, Mariangela; Ocadlikova, Darina; Sangaletti, Sabina; Trabanelli, Sara; De Marchi, Elena; ...Orioli, Elisa; Pegoraro, Anna; Portararo, Paola; Jandus, Camilla; Bontadini, Andrea; Redavid, Annarita; Salvestrini, Valentina; Romero, Pedro; Colombo, Mario P.; Di Virgilio, Francesco; Cavo, Michele; Adinolfi, Elena; Curti, Antonio | 2017-01-01 | FRONTIERS IN IMMUNOLOGY | - | 1.01 Articolo in rivista | fimmu-08-01918.pdf |
| CD103 marks a subset of human CD34<sup>+</sup>-derived langerin<sup>+</sup> dendritic cells that induce T-regulatory cells via indoleamine 2,3-dioxygenase-1 | Ocadlikova, Darina; Trabanelli, Sara; Salvestrini, Valentina; Ciciarello, Marilena; Evangelisti, ...Cecilia; Lecciso, MARIANGELA STEFANIA; Sabattini, Elena; Righi, Simona; Piccioli, Milena; Pileri, Stefano; Lemoli, ROBERTO MASSIMO; Curti, Antonio | 2015-01-01 | EXPERIMENTAL HEMATOLOGY | - | 1.01 Articolo in rivista | - |
| Corrigendum: Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells (Front. Oncol, (2020), 10, (1225), 10.3389/fonc.2020.01225) | Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.;... De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A. | 2021-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | fonc-11-668460 (1).pdf |
| Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells | Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.;... De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A. | 2020-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells.pdf; 5072249.zip |
| Deregulated expression of miR-29a-3p, miR-494-3p and miR-660-5p affects sensitivity to tyrosine kinase inhibitors in CML leukemic stem cells | Salati, Simona; Salvestrini, Valentina; Carretta, Chiara; Genovese, Elena; Rontauroli, Sebastiano...; Zini, Roberta; Rossi, Chiara; Ruberti, Samantha; Bianchi, Elisa; Barbieri, Greta; Curti, Antonio; Castagnetti, Fausto; Gugliotta, Gabriele; Rosti, Gianantonio; Bergamaschi, Micaela; Tafuri, Agostino; Tagliafico, Enrico | 2017-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Differential proteomic profile of leukemic CD34+ progenitor cells from chronic myeloid leukemia patients | Ricciardi, Maria Rosaria; Salvestrini, Valentina; Licchetta, Roberto; Mirabilii, Simone; Forcato,... Mattia; Gugliotta, Gabriele; Salati, Simona; Castagnetti, Fausto; Rosti, Gianantonio; Breccia, Massimo; Alimena, Giuliana; Manfredini, Rossella; Bicciato, Silvio; Lemoli, Roberto Massimo; Tafuri, Agostino* | 2018-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Extracellular ATP exerts opposite effects on activated and regulatory CD4 + T cells via purinergic P2 receptor activation | Trabanelli S; Ocadlíková D;Gulinelli S;Curti A;Salvestrini V; de Paula Vieira R;Idzko M;Di Virgil...io F; Ferrari D;Lemoli R.M. | 2012-01-01 | JOURNAL OF IMMUNOLOGY | - | 1.01 Articolo in rivista | - |
| Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells | Salvestrini, Valentina; Orecchioni, Stefania; Talarico, Giovanna; Reggiani, Francesca; Mazzetti, ...Cristina; Bertolini, Francesco; Orioli, Elisa; Adinolfi, Elena; Di Virgilio, Francesco; Pezzi, Annalisa; Cavo, Michele; Lemoli, Roberto M.; Curti, Antonio | 2017-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Extracellular purines promote the differentiation of human bone marrow-derived mesenchymal stem cells to the osteogenic and adipogenic lineages. | Ciciarello M; Zini R; Rossi L; Salvestrini V; Ferrari D; Manfredini R; Lemoli RM. | 2013-01-01 | STEM CELLS AND DEVELOPMENT | - | 1.01 Articolo in rivista | - |
| IL-18 and VEGF-A trigger type 2 innate lymphoid cell accumulation and pro-tumoral function in chronic myeloid leukemia | Fiordi, Benedetta; Salvestrini, Valentina; Gugliotta, Gabriele; Castagnetti, Fausto; Curti, Anton...io; Speiser, Daniel E.; Marcenaro, Emanuela; Jandus, Camilla; Trabanelli, Sara | 2023-01-01 | HAEMATOLOGICA | - | 1.01 Articolo in rivista | - |
| Immunosenescence and immunotherapy in elderly acute myeloid leukemia patients: Time for a biology-driven approach | Isidori, Alessandro*; Loscocco, Federica; Ciciarello, Marilena; Corradi, Giulia; Lecciso, Mariang...ela; Ocadlikova, Darina; Parisi, Sarah; Salvestrini, Valentina; Amadori, Sergio; Visani, Giuseppe; Curti, Antonio | 2018-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-10-00211.pdf |
| Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells. |
Curti A; Trabanelli S; Onofri C; Aluigi M; Salvestrini V; Ocadlikova D; Evangelisti C; Rutella S...; De Cristofaro R; Ottaviani E; Baccarani M; Lemoli RM. |
2010-01-01 | HAEMATOLOGICA | - | 1.01 Articolo in rivista | Indoleamine 2,3-Dioxygenase-Expressing Leukemic Dendritic Cells.pdf; 025924.Curti_suppl.pdf |
| Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells. | Curti A; Pandolfi S; Valzasina B; Aluigi M; Isidori A; Ferri E; Salvestrini V; Bonanno G; Rutella... S; Durelli I; Horenstein AL; Fiore F; Massaia M; Colombo MP; Baccarani M; Lemoli RM. | 2007-01-01 | BLOOD | - | 1.01 Articolo in rivista | - |
| Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34- cell population with intrinsic resistance to imatinib. | Lemoli RM; Salvestrini V; Bianchi E; Bertolini F; Fogli M; Amabile M; Tafuri A; Salati S; Zini R;... Testoni N; Rabascio C; Rossi L; Martin-Padura I; Castagnetti F; Marighetti P; Martinelli G; Baccarani M; Ferrari S; Manfredini R. | 2009-01-01 | BLOOD | - | 1.01 Articolo in rivista | - |
| Obesity may accelerate the aging process | Salvestrini V.; Sell C.; Lorenzini A. | 2019-01-01 | FRONTIERS IN ENDOCRINOLOGY | - | 1.01 Articolo in rivista | Obesity accelerates aging SALVESTRINI.pdf |
| PGE2-induced IDO1 inhibits the capacity of fully mature DCs to elicit an in vitro antileukemic immune response | Trabanelli, Sara; Lecciso, Mariangela; Salvestrini, Valentina; Cavo, Michele; Očadlíková, Darina;... Lemoli, Roberto M; Curti, Antonio | 2015-01-01 | JOURNAL OF IMMUNOLOGY RESEARCH | - | 1.01 Articolo in rivista | - |
| Phospholipase C beta1 (PI-PLCbeta1)/Cyclin D3/protein kinase C (PKC) alpha signaling modulation during iron-induced oxidative stress in myelodysplastic syndromes (MDS) | Alessandra Cappellini, Sara Mongiorgi, Carlo Finelli, Antonietta Fazio, Stefano Ratti, Maria Vitt...oria Marvi, Antonio Curti, Valentina Salvestrini, Andrea Pellagatti, Anna Maria Billi, Pann-Ghill Suh, James A. McCubrey, Jacqueline Boultwood, Lucia Manzoli, Lucio Cocco, Matilde Y. Follo | 2020-01-01 | THE FASEB JOURNAL | - | 1.01 Articolo in rivista | The FASEB Journal - 2020 - Cappellini - Phospholipase C beta1 PI‐PLCbeta1 Cyclin D3 protein kinase C PKC alpha.pdf |
| Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice. |
Salvestrini V.; Zini R.; Rossi L.; Gulinelli S.; Manfredini R.; Bianchi E.; Piacibello W.; Caione... L.; Migliardi G.; Ricciardi M.R.; Tafuri A.; Romano M.; Salati S.; Di Virgilio F.; Ferrari S.; Baccarani M.; Ferrari D.; Lemoli R.M. |
2012-01-01 | BLOOD | - | 1.01 Articolo in rivista | - |
| Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines. |
Ferrari D; Gulinelli S; Salvestrini V; Lucchetti G; Zini R; Manfredini R; Caione L; Piacibello W...; Ciciarello M; Rossi L; Idzko M; Ferrari S; Di Virgilio F; Lemoli R.M. |
2011-01-01 | EXPERIMENTAL HEMATOLOGY | - | 1.01 Articolo in rivista | - |