GHELLI, ANNA MARIA
GHELLI, ANNA MARIA
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Docenti di ruolo di IIa fascia
A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16.
2011 Carelli V.; Schimpf S.; Fuhrmann N.; Valentino M.L.; Zanna C.; Iommarini L.; Papke M.; Schaich S.; Tippmann S.; Baumann B.; Barboni P.; Longanesi L.; Rugolo M.; Ghelli A.; Alavi M.V.; Youle R.J.; Bucchi L.; Carroccia R.; Giannoccaro M.P.; Tonon C.; Lodi R.; Cenacchi G.; Montagna P.; Liguori R.; Wissinger B.
A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function
2011 Gasparre G; Kurelac I; Capristo M; Iommarini L; Ghelli A; Ceccarelli C; Nicoletti G; Nanni P; De Giovanni C; Scotlandi K; Betts CM; Carelli V; Lollini PL; Romeo G; Rugolo M; Porcelli AM
A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance.
2014 Carossa V;Ghelli A;Tropeano CV;Valentino ML;Iommarini L;Maresca A;Caporali L;Morgia CL;Liguori R;Barboni P;Carbonelli M;Rizzo G;Tonon C;Lodi R;Martinuzzi A;Nardo VD;Rugolo M;Ferretti L;Gandini F;Pala M;Achilli A;Olivieri A;Torroni A;Carelli V
AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations
2004 A.M.Porcelli; C. Zanna; A. Montanaro; V.Carelli; A.Ghelli; M.Rugolo
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder
2012 Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; Gasparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M.
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells.
2009 G.Gasparre; L. Iommarini; A.M. Porcelli; M. Lang; G.G. Ferri; I.Kurelac; E. Mariani; L.F. Pennisi; E. Pasquini; G. Pasquinelli; A. Ghelli; E. Bonora; C. Ceccarelli; M. Rugolo; N. Salfi; G. Romeo; V. Carelli.
Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance
2004 A.M. PORCELLI; A. GHELLI; C. ZANNA; P. VALENTE; S. FERRONI; M. RUGOLO
ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis
2004 A. Ghelli; C. Zanna; A.M. Porcelli; V. Carelli; M. Rugolo
Bioenergetics shapes cellular death pathways in Leber’s hereditary optic neuropathy: a model of mitochondrial neurodegeneration
2004 CARELLI V; RUGOLO M; SGARBI G; GHELLI A; ZANNA C; BARACCA A; LENAZ G; NAPOLI E; MARTINUZZI A; SOLAINI G.
Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G.
2005 ZANNA C.; GHELLI A.; PORCELLI AM.; MARTINUZZI A.; Carelli V.; RUGOLO M.
Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations
2004 C.Zanna; A.M.Porcelli; A.Ghelli; V.Carelli; A.Martinuzzi; M.Rugolo
Cigarette toxicity triggers Leber's hereditary optic neuropathy by affecting mtDNA copy number, oxidative phosphorylation and ROS detoxification pathways
2015 Giordano, L; Deceglie, S; D'Adamo, P; Valentino, M L; La Morgia, C; Fracasso, F; Roberti, M; Cappellari, M; Petrosillo, G; Ciaravolo, S; Parente, D; Giordano, C; Maresca, A; Iommarini, L; Del Dotto, V; Ghelli, A M; Salomao, S R; Berezovsky, A; Belfort, R; Sadun, A A; Carelli, V; Loguercio Polosa, P; Cantatore, P
Complex II phosphorylation is triggered by unbalanced redox homeostasis in cells lacking complex III
2018 Tropeano, Concetta Valentina; Fiori, Jessica; Carelli, Valerio; Caporali, Leonardo; Daldal, Fevzi; Ghelli, Anna Maria; Rugolo, Michela
Cybrid studies establish the causal link between the mtDNA m.3890G>A/MT-ND1 mutation and optic atrophy with bilateral brainstem lesions.
2013 Caporali L;Ghelli AM;Iommarini L;Maresca A;Valentino ML;La Morgia C;Liguori R;Zanna C;Barboni P;De Nardo V;Martinuzzi A;Rizzo G;Tonon C;Lodi R;Calvaruso MA;Cappelletti M;Porcelli AM;Achilli A;Pala M;Torroni A;Carelli V
Cybrids with mtDNA mutations causing Leber’s hereditary optic neuropathy are sensitized to apoptotic death induced by a mitochondrial oxidative stress
2006 A. M. Ghelli; C. Zanna; V. Carelli; A. Martinuzzi; M. Rugolo
Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III
2006 BONORA E.; PORCELLI A.M.; GASPARRE G.; BIONDI A.; GHELLI A.; CARELLI V.; BARACCA A.; TALLINI G.; MARTINUZZI A.; LENAZ G.; RUGOLO M.; ROMEO G.
Determination of mitochondrial fusion in fibroblasts from dominant optic atrophy patients bearing the c.2708delttag OPA1 mutation
2006 C. Zanna; A. Ghelli; A. M.Porcelli; M. Karbowski; R.J. Youle; V. Carelli; M. Rugolo
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment
2014 L. Iommarini;I. Kurelac;M. Capristo;M. A. Calvaruso;V. Giorgio;C. Bergamini;A. Ghelli;P. Nanni;C. De Giovanni;V. Carelli;R. Fato;P. L. Lollini;M. Rugolo;G. Gasparre;A. M. Porcelli
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumours.
2007 Gasparre G.; Porcelli A.M.; Bonora E.; Pennisi L.F.; Toller M.; Iommarini L.; Ghelli A.; Moretti M.; Betts C.M.; Martinelli G.N.; Ceroni A.R.; Curcio F.; Carelli V.; Rugolo M.; Tallini G.; Romeo G.
Dominant Optic Atrophy (DOA) and Sensorineural Hearing Loss: Clinical, Biochemical, Spectroscopic and Molecular Genetic Study of a Large Italian Pedigree Linked to a New Locus on Chromosome 16
2007 V. Carelli; S. Schimpf; M. L. Valentino; N. Fuhrmann; M. Papke; S. Schaich; S. Tippmann; B. Baumann; P. Barboni; A. Ghelli; L. Bucchi; R. Lodi; B. Barbiroli; R. Liguori; R. Carroccia; M. Villanova; P. Montagna; A. Baruzzi; B. Wissinger
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16. | Carelli V.; Schimpf S.; Fuhrmann N.; Valentino M.L.; Zanna C.; Iommarini L.; Papke M.; Schaich S....; Tippmann S.; Baumann B.; Barboni P.; Longanesi L.; Rugolo M.; Ghelli A.; Alavi M.V.; Youle R.J.; Bucchi L.; Carroccia R.; Giannoccaro M.P.; Tonon C.; Lodi R.; Cenacchi G.; Montagna P.; Liguori R.; Wissinger B. | 2011-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function | Gasparre G; Kurelac I; Capristo M; Iommarini L; Ghelli A; Ceccarelli C; Nicoletti G; Nanni P; De ...Giovanni C; Scotlandi K; Betts CM; Carelli V; Lollini PL; Romeo G; Rugolo M; Porcelli AM | 2011-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance. | Carossa V;Ghelli A;Tropeano CV;Valentino ML;Iommarini L;Maresca A;Caporali L;Morgia CL;Liguori R;...Barboni P;Carbonelli M;Rizzo G;Tonon C;Lodi R;Martinuzzi A;Nardo VD;Rugolo M;Ferretti L;Gandini F;Pala M;Achilli A;Olivieri A;Torroni A;Carelli V | 2014-01-01 | HUMAN MUTATION | - | 1.01 Articolo in rivista | - |
| AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations | A.M.Porcelli; C. Zanna; A. Montanaro; V.Carelli; A.Ghelli; M.Rugolo | 2004-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder | Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; G...asparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M. | 2012-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 4.02 Riassunto (Abstract) | - |
| An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells. | G.Gasparre; L. Iommarini; A.M. Porcelli; M. Lang; G.G. Ferri; I.Kurelac; E. Mariani; L.F. Pennisi...; E. Pasquini; G. Pasquinelli; A. Ghelli; E. Bonora; C. Ceccarelli; M. Rugolo; N. Salfi; G. Romeo; V. Carelli. | 2009-01-01 | HUMAN MUTATION | - | 1.01 Articolo in rivista | - |
| Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance | A.M. PORCELLI; A. GHELLI; C. ZANNA; P. VALENTE; S. FERRONI; M. RUGOLO | 2004-01-01 | CELL DEATH AND DIFFERENTIATION | - | 1.01 Articolo in rivista | - |
| ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis | A. Ghelli; C. Zanna; A.M. Porcelli; V. Carelli; M. Rugolo | 2004-01-01 | - | Dipartimento Biologia Ev. SP. | 4.02 Riassunto (Abstract) | - |
| Bioenergetics shapes cellular death pathways in Leber’s hereditary optic neuropathy: a model of mitochondrial neurodegeneration | CARELLI V; RUGOLO M; SGARBI G; GHELLI A; ZANNA C; BARACCA A; LENAZ G; NAPOLI E; MARTINUZZI A; SOL...AINI G. | 2004-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 1.01 Articolo in rivista | - |
| Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G. | ZANNA C.; GHELLI A.; PORCELLI AM.; MARTINUZZI A.; Carelli V.; RUGOLO M. | 2005-01-01 | APOPTOSIS | - | 1.01 Articolo in rivista | - |
| Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations | C.Zanna; A.M.Porcelli; A.Ghelli; V.Carelli; A.Martinuzzi; M.Rugolo | 2004-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Cigarette toxicity triggers Leber's hereditary optic neuropathy by affecting mtDNA copy number, oxidative phosphorylation and ROS detoxification pathways | Giordano, L; Deceglie, S; D'Adamo, P; Valentino, M L; La Morgia, C; Fracasso, F; Roberti, M; Capp...ellari, M; Petrosillo, G; Ciaravolo, S; Parente, D; Giordano, C; Maresca, A; Iommarini, L; Del Dotto, V; Ghelli, A M; Salomao, S R; Berezovsky, A; Belfort, R; Sadun, A A; Carelli, V; Loguercio Polosa, P; Cantatore, P | 2015-01-01 | CELL DEATH & DISEASE | - | 1.01 Articolo in rivista | Cigarette toxicity triggers Leber's hereditary optic neuropathy.pdf; Supplementary information.zip |
| Complex II phosphorylation is triggered by unbalanced redox homeostasis in cells lacking complex III | Tropeano, Concetta Valentina; Fiori, Jessica; Carelli, Valerio; Caporali, Leonardo; Daldal, Fevzi...; Ghelli, Anna Maria; Rugolo, Michela | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 1.01 Articolo in rivista | - |
| Cybrid studies establish the causal link between the mtDNA m.3890G>A/MT-ND1 mutation and optic atrophy with bilateral brainstem lesions. | Caporali L;Ghelli AM;Iommarini L;Maresca A;Valentino ML;La Morgia C;Liguori R;Zanna C;Barboni P;D...e Nardo V;Martinuzzi A;Rizzo G;Tonon C;Lodi R;Calvaruso MA;Cappelletti M;Porcelli AM;Achilli A;Pala M;Torroni A;Carelli V | 2013-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE | - | 1.01 Articolo in rivista | - |
| Cybrids with mtDNA mutations causing Leber’s hereditary optic neuropathy are sensitized to apoptotic death induced by a mitochondrial oxidative stress | A. M. Ghelli; C. Zanna; V. Carelli; A. Martinuzzi; M. Rugolo | 2006-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III | BONORA E.; PORCELLI A.M.; GASPARRE G.; BIONDI A.; GHELLI A.; CARELLI V.; BARACCA A.; TALLINI G.; ...MARTINUZZI A.; LENAZ G.; RUGOLO M.; ROMEO G. | 2006-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Determination of mitochondrial fusion in fibroblasts from dominant optic atrophy patients bearing the c.2708delttag OPA1 mutation | C. Zanna; A. Ghelli; A. M.Porcelli; M. Karbowski; R.J. Youle; V. Carelli; M. Rugolo | 2006-01-01 | - | s. n. | 4.02 Riassunto (Abstract) | - |
| Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment | L. Iommarini;I. Kurelac;M. Capristo;M. A. Calvaruso;V. Giorgio;C. Bergamini;A. Ghelli;P. Nanni;C.... De Giovanni;V. Carelli;R. Fato;P. L. Lollini;M. Rugolo;G. Gasparre;A. M. Porcelli | 2014-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumours. | Gasparre G.; Porcelli A.M.; Bonora E.; Pennisi L.F.; Toller M.; Iommarini L.; Ghelli A.; Moretti ...M.; Betts C.M.; Martinelli G.N.; Ceroni A.R.; Curcio F.; Carelli V.; Rugolo M.; Tallini G.; Romeo G. | 2007-01-01 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | - | 1.01 Articolo in rivista | - |
| Dominant Optic Atrophy (DOA) and Sensorineural Hearing Loss: Clinical, Biochemical, Spectroscopic and Molecular Genetic Study of a Large Italian Pedigree Linked to a New Locus on Chromosome 16 | V. Carelli; S. Schimpf; M. L. Valentino; N. Fuhrmann; M. Papke; S. Schaich; S. Tippmann; B. Bauma...nn; P. Barboni; A. Ghelli; L. Bucchi; R. Lodi; B. Barbiroli; R. Liguori; R. Carroccia; M. Villanova; P. Montagna; A. Baruzzi; B. Wissinger | 2007-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |