Sfoglia per Autore
A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma
2012 Giovanni Perini; Emanuele Valli; Samuele Gherardi; Simone Di Giacomo; Giorgio Milazzo; Timothy R. Wagenaar; Michael R. Green
Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression
2014 Liu, Pei Y.; Erriquez, Daniela; Marshall, Glenn M.; Tee, Andrew E.; Polly, Patsie; Wong, Mathew; Liu, Bing; Bell, Jessica L.; Zhang, Xu D.; Milazzo, Giorgio; Cheung, Belamy B.; Fox, Archa; Swarbrick, Alexander; Hüttelmaier, Stefan; Kavallaris, Maria; Perini, Giovanni; Mattick, John S.; Dinger, Marcel E.; Liu, Tao
Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma
2015 Amente, Stefano; Milazzo, Giorgio; Sorrentino, Maria Cristina; Ambrosio, Susanna; Di Palo, Giacomo; Lania, Luigi; Perini, Giovanni; Majello, Barbara
SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma
2015 Evans, Laura; Chen, Lindi; Milazzo, Giorgio; Gherardi, Samuele; Perini, Giovanni; Willmore, Elaine; Newell, David R.; Tweddle, Deborah A.
Growth of Rhodococcus sp. strain BCP1 on gaseous n-alkanes: new metabolic insights and transcriptional analysis of two soluble di-iron monooxygenase genes
2015 Martina Cappelletti;Alessandro Presentato;Giorgio Milazzo;Raymond J. Turner;Stefano Fedi;Dario Frascari;Davide Zannoni
WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma
2015 Sun, Yuting; Bell, Jessica L; Carter, Daniel; Gherardi, Samuele; Poulos, Rebecca C; Milazzo, Giorgio; Wong, Jason W H; Al-Awar, Rima; Tee, Andrew E; Liu, Pei Y; Liu, Bing; Atmadibrata, Bernard; Wong, Matthew; Trahair, Toby; Zhao, Quan; Shohet, Jason M; Haupt, Ygal; Schulte, Johannes H; Brown, Peter J; Arrowsmith, Cheryl H; Vedadi, Masoud; Mackenzie, Karen L; Hüttelmaier, Stefan; Perini, Giovanni; Marshall, Glenn M; Braithwaite, Antony; Liu, Tao
MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4
2016 Xue, Chengyuan; Yu, Denise M T; Gherardi, Samuele; Koach, Jessica; Milazzo, Giorgio; Gamble, Laura; Liu, Bing; Valli, Emanuele; Russell, Amanda J; London, Wendy B; Liu, Tao; Cheung, Belamy B; Marshall, Glenn M; Perini, Giovanni; Haber, Michelle; Norris, Murray D; Xue, Chengyuan; Yu, Denise M T; Gherardi, Samuele; Koach, Jessica; Milazzo, Giorgio; Gamble, Laura; Liu, Bing; Valli, Emanuele; Russell, Amanda J; London, Wendy B; Liu, Tao; Cheung, Belamy B; Marshall, Glenn M; Perini, Giovanni; Haber, Michelle; Norris, Murray D
Letting the breaks off MYCN
2016 Perini, Giovanni; Milazzo, Giorgio; Narayan, Nisha; Ekert, Paul G
The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription
2017 Wong, Matthew; Tee, Andrew E.L.; Milazzo, Giorgio; Bell, Jessica L.; Poulos, Rebecca C.; Atmadibrata, Bernard; Sun, Yuting; Jing, Duohui; Ho, Nicholas; Ling, Dora; Liu, Pei Yan; Zhang, Xu Dong; Hüttelmaier, Stefan; Wong, Jason W.H.; Wang, Jenny; Polly, Patsie; Perini, Giovanni; Scarlett, Christopher J.; Liu, Tao
Aerobic Growth of Rhodococcus aetherivorans BCP1 Using Selected Naphthenic Acids as the Sole Carbon and Energy Sources
2018 Presentato, Alessandro; Cappelletti, Martina; Sansone, Anna; Ferreri, Carla; Piacenza, Elena; Demeter, Marc A.; Crognale, Silvia; Petruccioli, Maurizio; Milazzo, Giorgio; Fedi, Stefano; Steinbüchel, Alexander; Turner, Raymond J.; Zannoni, Davide
MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma
2018 Agarwal, Saurabh; Milazzo, Giorgio; Rajapakshe, Kimal; Bernardi, Ronald; Chen, Zaowen; Barberi, Eveline; Koster, Jan; Perini, Giovanni; Coarfa, Cristian; Shohet, Jason M.*
MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma
2018 Ferrucci, Francesca; Ciaccio, Roberto; Monticelli, Sara; Pigini, Paolo; di Giacomo, Simone; Purgato, Stefania; Erriquez, Daniela; Bernardoni, Roberto; Norris, Murray; Haber, Michelle; Milazzo, Giorgio; Perini, Giovanni
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma
2019 Laura D. Gamble, Stefania Purgato, Jayne Murray, Lin Xiao, Denise M. T. Yu, Kimberley M. Hanssen, Federico M. Giorgi, Daniel R. Carter, Andrew J. Gifford, Emanuele Valli, Giorgio Milazzo, Alvin Kamili, Chelsea Mayoh, Bing Liu, Georgina Eden, Sara Sarraf, Sophie Allan, Simone Di Giacomo, Claudia L. Flemming, Amanda J. Russell, Belamy B. Cheung, Andre Oberthuer, Wendy B. London, Matthias Fischer, Toby N. Trahair, Jamie I. Fletcher, Glenn M. Marshall, David S. Ziegler, Michael D. Hogarty, Mark R. Burns, Giovanni Perini, Murray D. Norris, and Michelle Haber
Drugging MYCN oncogenic signalling through the MYCN-PA2G4 binding interface
2019 Koach, Jessica; Holien, Jessica K; Massudi, Hassina; Carter, Daniel R; Ciampa, Olivia C; Herath, Mika; Lim, Taylor; Seneviratne, Janith A; Milazzo, Giorgio; Murray, Jayne E; McCarroll, Joshua A; Liu, Bing; Mayoh, Chelsea; Keenan, Bryce; Stevenson, Brendan W; Gorman, Michael A; Bell, Jessica L; Doughty, Larissa; Hüttelmaier, Stefan; Oberthuer, Andre; Fischer, Matthias; Gifford, Andrew J; Liu, Tao; Zhang, Xiaoling; Zhu, Shizhen; Gustafson, W Clay; Haber, Michelle; Norris, Murray D; Fletcher, Jamie I; Perini, Giovanni; Parker, Michael W; Cheung, Belamy B; Marshall, Glenn M
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35
2019 Liu, Pei Y; Tee, Andrew E; Milazzo, Giorgio; Hannan, Katherine M; Maag, Jesper; Mondal, Sujanna; Atmadibrata, Bernard; Bartonicek, Nenad; Peng, Hui; Ho, Nicholas; Mayoh, Chelsea; Ciaccio, Roberto; Sun, Yuting; Henderson, Michelle J; Gao, Jixuan; Everaert, Celine; Hulme, Amy J; Wong, Matthew; Lan, Qing; Cheung, Belamy B; Shi, Leming; Wang, Jenny Y; Simon, Thorsten; Fischer, Matthias; Zhang, Xu D; Marshall, Glenn M; Norris, Murray D; Haber, Michelle; Vandesompele, Jo; Li, Jinyan; Mestdagh, Pieter; Hannan, Ross D; Dinger, Marcel E; Perini, Giovanni; Liu, Tao
Unveiling Early Differentiation Induced by Histone Deacetylase Inhibitors in Neuroblastoma Cell Lines: A Single-Cell Transcriptomics Approach
2019 Giorgio MIlazzo, Daniele Mercatelli, Giovanni Perini, Federico M. Giorgi
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma
2019 Wong M.; Sun Y.; Xi Z.; Milazzo G.; Poulos R.C.; Bartenhagen C.; Bell J.L.; Mayoh C.; Ho N.; Tee A.E.; Chen X.; Li Y.; Ciaccio R.; Liu P.Y.; Jiang C.C.; Lan Q.; Jayatilleke N.; Cheung B.B.; Haber M.; Norris M.D.; Zhang X.D.; Marshall G.M.; Wang J.Y.; Huttelmaier S.; Fischer M.; Wong J.W.H.; Xu H.; Perini G.; Dong Q.; George R.E.; Liu T.
Histone deacetylases (HDACs): Evolution, specificity, role in transcriptional complexes, and pharmacological actionability
2020 Milazzo G.; Mercatelli D.; Di Muzio G.; Triboli L.; De Rosa P.; Perini G.; Giorgi F.M.
Restoration of the molecular clock is tumor suppressive in neuroblastoma
2021 Moreno-Smith M.; Milazzo G.; Tao L.; Fekry B.; Zhu B.; Mohammad M.A.; Di Giacomo S.; Borkar R.; Reddy K.R.K.; Capasso M.; Vasudevan S.A.; Sumazin P.; Hicks J.; Putluri N.; Perini G.; Eckel-Mahan K.; Burris T.P.; Barbieri E.
A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma
2021 Gamble L.D.; Purgato S.; Henderson M.J.; Di Giacomo S.; Russell A.J.; Pigini P.; Murray J.; Valli E.; Milazzo G.; Giorgi F.M.; Cowley M.; Ashton L.J.; Bhalshankar J.; Schleiermacher G.; Rihani A.; Van Maerken T.; Vandesompele J.; Speleman F.; Versteeg R.; Koster J.; Eggert A.; Noguera R.; Stallings R.L.; Tonini G.P.; Fong K.; Vaksman Z.; Diskin S.J.; Maris J.M.; London W.B.; Marshall G.M.; Ziegler D.S.; Hogarty M.D.; Perini G.; Norris M.D.; Haber M.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma | Giovanni Perini; Emanuele Valli; Samuele Gherardi; Simone Di Giacomo; Giorgio Milazzo; Timothy R.... Wagenaar; Michael R. Green | 2012-01-01 | - | - | 4.03 Poster | - |
| Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression | Liu, Pei Y.; Erriquez, Daniela; Marshall, Glenn M.; Tee, Andrew E.; Polly, Patsie; Wong, Mathew; ...Liu, Bing; Bell, Jessica L.; Zhang, Xu D.; Milazzo, Giorgio; Cheung, Belamy B.; Fox, Archa; Swarbrick, Alexander; Hüttelmaier, Stefan; Kavallaris, Maria; Perini, Giovanni; Mattick, John S.; Dinger, Marcel E.; Liu, Tao | 2014-01-01 | JOURNAL OF THE NATIONAL CANCER INSTITUTE | - | 1.01 Articolo in rivista | - |
| Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma | Amente, Stefano; Milazzo, Giorgio; Sorrentino, Maria Cristina; Ambrosio, Susanna; Di Palo, Giacom...o; Lania, Luigi; Perini, Giovanni; Majello, Barbara | 2015-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | Milazzo,Perini-oncotarget-v6i16-3990.pdf |
| SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma | Evans, Laura; Chen, Lindi; Milazzo, Giorgio; Gherardi, Samuele; Perini, Giovanni; Willmore, Elain...e; Newell, David R.; Tweddle, Deborah A. | 2015-01-01 | CANCER LETTERS | - | 1.01 Articolo in rivista | - |
| Growth of Rhodococcus sp. strain BCP1 on gaseous n-alkanes: new metabolic insights and transcriptional analysis of two soluble di-iron monooxygenase genes | Martina Cappelletti;Alessandro Presentato;Giorgio Milazzo;Raymond J. Turner;Stefano Fedi;Dario Fr...ascari;Davide Zannoni | 2015-01-01 | FRONTIERS IN MICROBIOLOGY | - | 1.01 Articolo in rivista | - |
| WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma | Sun, Yuting; Bell, Jessica L; Carter, Daniel; Gherardi, Samuele; Poulos, Rebecca C; Milazzo, Gior...gio; Wong, Jason W H; Al-Awar, Rima; Tee, Andrew E; Liu, Pei Y; Liu, Bing; Atmadibrata, Bernard; Wong, Matthew; Trahair, Toby; Zhao, Quan; Shohet, Jason M; Haupt, Ygal; Schulte, Johannes H; Brown, Peter J; Arrowsmith, Cheryl H; Vedadi, Masoud; Mackenzie, Karen L; Hüttelmaier, Stefan; Perini, Giovanni; Marshall, Glenn M; Braithwaite, Antony; Liu, Tao | 2015-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | Cancer Res-2015-Sun-5143-54.pdf |
| MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4 | Xue, Chengyuan; Yu, Denise M T; Gherardi, Samuele; Koach, Jessica; Milazzo, Giorgio; Gamble, Laur...a; Liu, Bing; Valli, Emanuele; Russell, Amanda J; London, Wendy B; Liu, Tao; Cheung, Belamy B; Marshall, Glenn M; Perini, Giovanni; Haber, Michelle; Norris, Murray D; Xue, Chengyuan; Yu, Denise M T; Gherardi, Samuele; Koach, Jessica; Milazzo, Giorgio; Gamble, Laura; Liu, Bing; Valli, Emanuele; Russell, Amanda J; London, Wendy B; Liu, Tao; Cheung, Belamy B; Marshall, Glenn M; Perini, Giovanni; Haber, Michelle; Norris, Murray D | 2016-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Letting the breaks off MYCN | Perini, Giovanni; Milazzo, Giorgio; Narayan, Nisha; Ekert, Paul G | 2016-01-01 | CELL DEATH AND DIFFERENTIATION | - | 1.01 Articolo in rivista | - |
| The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription | Wong, Matthew; Tee, Andrew E.L.; Milazzo, Giorgio; Bell, Jessica L.; Poulos, Rebecca C.; Atmadibr...ata, Bernard; Sun, Yuting; Jing, Duohui; Ho, Nicholas; Ling, Dora; Liu, Pei Yan; Zhang, Xu Dong; Hüttelmaier, Stefan; Wong, Jason W.H.; Wang, Jenny; Polly, Patsie; Perini, Giovanni; Scarlett, Christopher J.; Liu, Tao | 2017-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Aerobic Growth of Rhodococcus aetherivorans BCP1 Using Selected Naphthenic Acids as the Sole Carbon and Energy Sources | Presentato, Alessandro; Cappelletti, Martina; Sansone, Anna; Ferreri, Carla; Piacenza, Elena; Dem...eter, Marc A.; Crognale, Silvia; Petruccioli, Maurizio; Milazzo, Giorgio; Fedi, Stefano; Steinbüchel, Alexander; Turner, Raymond J.; Zannoni, Davide | 2018-01-01 | FRONTIERS IN MICROBIOLOGY | - | 1.01 Articolo in rivista | fmicb-09-00672-1.pdf |
| MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma | Agarwal, Saurabh; Milazzo, Giorgio; Rajapakshe, Kimal; Bernardi, Ronald; Chen, Zaowen; Barberi, E...veline; Koster, Jan; Perini, Giovanni; Coarfa, Cristian; Shohet, Jason M.* | 2018-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma | Ferrucci, Francesca; Ciaccio, Roberto; Monticelli, Sara; Pigini, Paolo; di Giacomo, Simone; Purga...to, Stefania; Erriquez, Daniela; Bernardoni, Roberto; Norris, Murray; Haber, Michelle; Milazzo, Giorgio; Perini, Giovanni | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA | - | 1.01 Articolo in rivista | - |
| Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma | Laura D. Gamble, Stefania Purgato, Jayne Murray, Lin Xiao, Denise M. T. Yu, Kimberley M. Hanssen,... Federico M. Giorgi, Daniel R. Carter, Andrew J. Gifford, Emanuele Valli, Giorgio Milazzo, Alvin Kamili, Chelsea Mayoh, Bing Liu, Georgina Eden, Sara Sarraf, Sophie Allan, Simone Di Giacomo, Claudia L. Flemming, Amanda J. Russell, Belamy B. Cheung, Andre Oberthuer, Wendy B. London, Matthias Fischer, Toby N. Trahair, Jamie I. Fletcher, Glenn M. Marshall, David S. Ziegler, Michael D. Hogarty, Mark R. Burns, Giovanni Perini, Murray D. Norris, and Michelle Haber | 2019-01-01 | SCIENCE TRANSLATIONAL MEDICINE | - | 1.01 Articolo in rivista | - |
| Drugging MYCN oncogenic signalling through the MYCN-PA2G4 binding interface | Koach, Jessica; Holien, Jessica K; Massudi, Hassina; Carter, Daniel R; Ciampa, Olivia C; Herath, ...Mika; Lim, Taylor; Seneviratne, Janith A; Milazzo, Giorgio; Murray, Jayne E; McCarroll, Joshua A; Liu, Bing; Mayoh, Chelsea; Keenan, Bryce; Stevenson, Brendan W; Gorman, Michael A; Bell, Jessica L; Doughty, Larissa; Hüttelmaier, Stefan; Oberthuer, Andre; Fischer, Matthias; Gifford, Andrew J; Liu, Tao; Zhang, Xiaoling; Zhu, Shizhen; Gustafson, W Clay; Haber, Michelle; Norris, Murray D; Fletcher, Jamie I; Perini, Giovanni; Parker, Michael W; Cheung, Belamy B; Marshall, Glenn M | 2019-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface.pdf |
| The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35 | Liu, Pei Y; Tee, Andrew E; Milazzo, Giorgio; Hannan, Katherine M; Maag, Jesper; Mondal, Sujanna; ...Atmadibrata, Bernard; Bartonicek, Nenad; Peng, Hui; Ho, Nicholas; Mayoh, Chelsea; Ciaccio, Roberto; Sun, Yuting; Henderson, Michelle J; Gao, Jixuan; Everaert, Celine; Hulme, Amy J; Wong, Matthew; Lan, Qing; Cheung, Belamy B; Shi, Leming; Wang, Jenny Y; Simon, Thorsten; Fischer, Matthias; Zhang, Xu D; Marshall, Glenn M; Norris, Murray D; Haber, Michelle; Vandesompele, Jo; Li, Jinyan; Mestdagh, Pieter; Hannan, Ross D; Dinger, Marcel E; Perini, Giovanni; Liu, Tao | 2019-01-01 | NATURE COMMUNICATIONS | - | 1.01 Articolo in rivista | The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35.pdf |
| Unveiling Early Differentiation Induced by Histone Deacetylase Inhibitors in Neuroblastoma Cell Lines: A Single-Cell Transcriptomics Approach | Giorgio MIlazzo, Daniele Mercatelli, Giovanni Perini, Federico M. Giorgi | 2019-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma | Wong M.; Sun Y.; Xi Z.; Milazzo G.; Poulos R.C.; Bartenhagen C.; Bell J.L.; Mayoh C.; Ho N.; Tee ...A.E.; Chen X.; Li Y.; Ciaccio R.; Liu P.Y.; Jiang C.C.; Lan Q.; Jayatilleke N.; Cheung B.B.; Haber M.; Norris M.D.; Zhang X.D.; Marshall G.M.; Wang J.Y.; Huttelmaier S.; Fischer M.; Wong J.W.H.; Xu H.; Perini G.; Dong Q.; George R.E.; Liu T. | 2019-01-01 | NATURE COMMUNICATIONS | - | 1.01 Articolo in rivista | JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma.pdf |
| Histone deacetylases (HDACs): Evolution, specificity, role in transcriptional complexes, and pharmacological actionability | Milazzo G.; Mercatelli D.; Di Muzio G.; Triboli L.; De Rosa P.; Perini G.; Giorgi F.M. | 2020-01-01 | GENES | - | 1.01 Articolo in rivista | genes-11-00556-v2_compressed.pdf |
| Restoration of the molecular clock is tumor suppressive in neuroblastoma | Moreno-Smith M.; Milazzo G.; Tao L.; Fekry B.; Zhu B.; Mohammad M.A.; Di Giacomo S.; Borkar R.; R...eddy K.R.K.; Capasso M.; Vasudevan S.A.; Sumazin P.; Hicks J.; Putluri N.; Perini G.; Eckel-Mahan K.; Burris T.P.; Barbieri E. | 2021-01-01 | NATURE COMMUNICATIONS | - | 1.01 Articolo in rivista | Myrthala Moreno-Smith et al.pdf |
| A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma | Gamble L.D.; Purgato S.; Henderson M.J.; Di Giacomo S.; Russell A.J.; Pigini P.; Murray J.; Valli... E.; Milazzo G.; Giorgi F.M.; Cowley M.; Ashton L.J.; Bhalshankar J.; Schleiermacher G.; Rihani A.; Van Maerken T.; Vandesompele J.; Speleman F.; Versteeg R.; Koster J.; Eggert A.; Noguera R.; Stallings R.L.; Tonini G.P.; Fong K.; Vaksman Z.; Diskin S.J.; Maris J.M.; London W.B.; Marshall G.M.; Ziegler D.S.; Hogarty M.D.; Perini G.; Norris M.D.; Haber M. | 2021-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-13-01807-v2.pdf |
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