Sfoglia per Autore
Comparison of raltegravir and elvitegravir on HIV-1 integrase catalytic reactions and on a series of drug-resistant integrase mutants
2008 Marinello J; Marchand C; Mott BT; Bain A; Thomas CJ; Pommier Y
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT
2009 Tumiatti V; Milelli A ; Minarini A; Micco M; Gasperi-Campani A; Roncuzzi L; Baiocchi D; Marinello J; Capranico G; Zini M; Stefanelli C; Melchiorre C
Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: Implications for physiological and therapeutic modulation of enzyme activity.
2010 G. Capranico; J. Marinello; L. Baranello
Electron Paramagnetic Resonance (EPR) Study of Spin-Labeled Camptothecin Derivatives: A Different Look of the Ternary Complex.
2011 Ricci A; Marinello J; Bortolus M; Sanchez A; Grandas A; Pedroso E; Pommier Y; Capranico G; Maniero AL; Zagotto G.
Characterization of novel antisense HIF-1α transcripts in human cancers
2011 Bertozzi Davide; Iurlaro Raffaella; Sordet Olivier; Marinello Jessica; Zaffaroni Nadia; Capranico Giovanni
Transcriptional Stress by Camptothecin: Mechanisms and Implications for the Drug Antitumor Activity
2012 Capranico G; Baranello L; Bertozzi D; Marinello J
Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II
2012 Manzo S. G.; Z.-L. Zhou; Y.-Q. Wang; J. Marinello; J.-X. He; Y.-C. Li; J. Ding; G. Capranico; Z.-H. Miao
Discovery of new antisense transcripts induced by camptothecin at CpG island promoters of human cells.
2012 Marinello Jessica; Susana Bueno; Stefano G Manzo; Roberta Ragazzini; Giovanni Chillemi; Giovanni Capranico
In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2.
2012 Fornari F.; Milazzo M.; Chieco P.; Negrini M.; Marasco E.; Capranico G.; Mantovani V.; Marinello J.; Sabbioni S.; Callegari E.; Cescon M.; Ravaioli M.; Croce C.M.; Bolondi L.; Gramantieri L.
Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation.
2013 Petronzi C; Festa M; Peduto A; Castellano M; Marinello J; Massa A; Capasso A; Capranico G; La Gatta A; De Rosa M; Caraglia M; Filosa R.
Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation
2013 J. Marinello;G. Chillemi;S. Bueno;S. G. Manzo;G. Capranico
Novel DNA Topoisomerase IIα Inhibitors from Combined Ligand- and Structure-Based Virtual Screening
2014 Malgorzata N. Drwal;Jessica Marinello;Stefano G. Manzo;Laurence P. G. Wakelin;Giovanni Capranico;Renate Griffith
The Natural Inhibitor of DNA Topoisomerase I, Camptothecin, Modulates HIF-1 alpha Activity by Changing miR Expression Patterns in Human Cancer Cells
2014 D. Bertozzi;J. Marinello;S. G. Manzo;F. Fornari;L. Gramantieri;G. Capranico
Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: A new opportunity in the targeting of G-rich DNA structures?
2016 Amato, Jussara; Pagano, Alessia; Cosconati, Sandro; Amendola, Giorgio; Fotticchia, Iolanda; Iaccarino, Nunzia; Marinello, Jessica; De Magis, Alessio; Capranico, Giovanni; Novellino, Ettore; Pagano, Bruno; Randazzo, Antonio
Dynamic effects of topoisomerase i inhibition on R-loops and short transcripts at active promoters
2016 Marinello, Jessica; Bertoncini, Stefania; Aloisi, Iris; Cristini, Agnese; Tagliazucchi, Guidantonio Malagoli; Forcato, Mattia; Sordet, Olivier; Capranico, Giovanni
G-quadruplex binders cause DNA damage by inducing R loops in human cancer cells.
2017 A. De Magis, S. G. Manzo, J. Marinello, R. Morigi, M. Rambaldi, O. Sodet, G. Capranico.
Type I DNA Topoisomerases
2017 Capranico, Giovanni; Marinello, Jessica; Chillemi, Giovanni
RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation
2017 Miglietta, Giulia; Cogoi, Susanna; Marinello, Jessica; Capranico, Giovanni; Tikhomirov, Alexander S.; Shchekotikhin, Andrey; Xodo, Luigi E.*
Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents
2018 R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, J. Marinello, G. Capranico, E. Novellino, A. Randazzo
Genome instability by G-quadruplex ligands are mediated by R-loops in human cancer cells
2018 Alessio De Magis, Stefano G. Manzo, Jessica Marinello, Marco Russo, Olivier Sordet, Rita Morigi, Giovanni Capranico
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Comparison of raltegravir and elvitegravir on HIV-1 integrase catalytic reactions and on a series of drug-resistant integrase mutants | Marinello J; Marchand C; Mott BT; Bain A; Thomas CJ; Pommier Y | 2008-01-01 | BIOCHEMISTRY | - | 1.01 Articolo in rivista | - |
| DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT | Tumiatti V; Milelli A ; Minarini A; Micco M; Gasperi-Campani A; Roncuzzi L; Baiocchi D; Marinello... J; Capranico G; Zini M; Stefanelli C; Melchiorre C | 2009-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: Implications for physiological and therapeutic modulation of enzyme activity. | G. Capranico; J. Marinello; L. Baranello | 2010-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER | - | 1.01 Articolo in rivista | - |
| Electron Paramagnetic Resonance (EPR) Study of Spin-Labeled Camptothecin Derivatives: A Different Look of the Ternary Complex. | Ricci A; Marinello J; Bortolus M; Sanchez A; Grandas A; Pedroso E; Pommier Y; Capranico G; Manier...o AL; Zagotto G. | 2011-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Characterization of novel antisense HIF-1α transcripts in human cancers | Bertozzi Davide; Iurlaro Raffaella; Sordet Olivier; Marinello Jessica; Zaffaroni Nadia; Capranico... Giovanni | 2011-01-01 | CELL CYCLE | - | 1.01 Articolo in rivista | - |
| Transcriptional Stress by Camptothecin: Mechanisms and Implications for the Drug Antitumor Activity | Capranico G; Baranello L; Bertozzi D; Marinello J | 2012-01-01 | - | Humana Press - Springer Science | 2.01 Capitolo / saggio in libro | - |
| Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II | Manzo S. G.; Z.-L. Zhou; Y.-Q. Wang; J. Marinello; J.-X. He; Y.-C. Li; J. Ding; G. Capranico; Z.-...H. Miao | 2012-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Discovery of new antisense transcripts induced by camptothecin at CpG island promoters of human cells. | Marinello Jessica; Susana Bueno; Stefano G Manzo; Roberta Ragazzini; Giovanni Chillemi; Giovanni ...Capranico | 2012-01-01 | - | Insubria University Press | 4.02 Riassunto (Abstract) | - |
| In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2. | Fornari F.; Milazzo M.; Chieco P.; Negrini M.; Marasco E.; Capranico G.; Mantovani V.; Marinello ...J.; Sabbioni S.; Callegari E.; Cescon M.; Ravaioli M.; Croce C.M.; Bolondi L.; Gramantieri L. | 2012-01-01 | JOURNAL OF PATHOLOGY | - | 1.01 Articolo in rivista | - |
| Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation. | Petronzi C; Festa M; Peduto A; Castellano M; Marinello J; Massa A; Capasso A; Capranico G; La Gat...ta A; De Rosa M; Caraglia M; Filosa R. | 2013-01-01 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation | J. Marinello;G. Chillemi;S. Bueno;S. G. Manzo;G. Capranico | 2013-01-01 | NUCLEIC ACIDS RESEARCH | - | 1.01 Articolo in rivista | - |
| Novel DNA Topoisomerase IIα Inhibitors from Combined Ligand- and Structure-Based Virtual Screening | Malgorzata N. Drwal;Jessica Marinello;Stefano G. Manzo;Laurence P. G. Wakelin;Giovanni Capranico;...Renate Griffith | 2014-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | - |
| The Natural Inhibitor of DNA Topoisomerase I, Camptothecin, Modulates HIF-1 alpha Activity by Changing miR Expression Patterns in Human Cancer Cells | D. Bertozzi;J. Marinello;S. G. Manzo;F. Fornari;L. Gramantieri;G. Capranico | 2014-01-01 | MOLECULAR CANCER THERAPEUTICS | - | 1.01 Articolo in rivista | - |
| Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: A new opportunity in the targeting of G-rich DNA structures? | Amato, Jussara; Pagano, Alessia; Cosconati, Sandro; Amendola, Giorgio; Fotticchia, Iolanda; Iacca...rino, Nunzia; Marinello, Jessica; De Magis, Alessio; Capranico, Giovanni; Novellino, Ettore; Pagano, Bruno; Randazzo, Antonio | 2016-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | - | 1.01 Articolo in rivista | - |
| Dynamic effects of topoisomerase i inhibition on R-loops and short transcripts at active promoters | Marinello, Jessica; Bertoncini, Stefania; Aloisi, Iris; Cristini, Agnese; Tagliazucchi, Guidanton...io Malagoli; Forcato, Mattia; Sordet, Olivier; Capranico, Giovanni | 2016-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | - |
| G-quadruplex binders cause DNA damage by inducing R loops in human cancer cells. | A. De Magis, S. G. Manzo, J. Marinello, R. Morigi, M. Rambaldi, O. Sodet, G. Capranico. | 2017-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Type I DNA Topoisomerases | Capranico, Giovanni; Marinello, Jessica; Chillemi, Giovanni | 2017-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation | Miglietta, Giulia; Cogoi, Susanna; Marinello, Jessica; Capranico, Giovanni; Tikhomirov, Alexander... S.; Shchekotikhin, Andrey; Xodo, Luigi E.* | 2017-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents | R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, ...J. Marinello, G. Capranico, E. Novellino, A. Randazzo | 2018-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Genome instability by G-quadruplex ligands are mediated by R-loops in human cancer cells |
Alessio De Magis, Stefano G. Manzo, Jessica Marinello, Marco Russo, Olivier Sordet, Rita Morigi,... Giovanni Capranico |
2018-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
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