Sfoglia per Autore
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents.
2008 Radi M; Crespan E; Botta G; Falchi F; Maga G; Manetti F; Corradi V; Mancini M; Santucci MA; Schenone S; Botta M.
Pharmacophore modeling and molecular docking led to the discovery of inhibitors of human immunodeficiency virus-1 replication targeting the human cellular aspartic acid-glutamic acid-alanine-aspartic acid box polypeptide 3
2008 Maga G.; Falchi F.; Garbelli A.; Belfiore A.; Witvrouw M.; Manetti F.; Botta M.
N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds
2008 Manetti F.; Falchi F.; Crespan E.; Schenone S.; Maga G.; Botta M.
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data
2009 Dreassi E.; Zizzari A.T.; Falchi F.; Schenone S.; Santucci A.; Maga G.; Botta M.
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors
2009 Falchi F.; Manetti F.; Carraro F.; Naldini A.; Maga G.; Crespan E.; Schenone S.; Bruno O.; Brullo C.; Botta M.
Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase
2010 Giovanni Maga, Federico Falchi, Anna Garbelli, Marco Radi, Stefania Paolucci, Fausto Baldanti, Maurizio Botta
Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: From docking false positives to ATP-noncompetitive inhibitors
2010 Radi M.; Crespan E.; Falchi F.; Bernardo V.; Zanoli S.; Manetti F.; Schenone S.; Maga G.; Botta M.
COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF
2011 RADI MARCO; BOTTA MAURIZIO; FALCHI FEDERICO; MAGA GIOVANNI; BALDANTI FAUSTO; PAOLUCCI STEFANIA
Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication
2011 Garbelli A.; Radi M.; Falchi F.; Beermann S.; Zanoli S.; Manetti F.; Dietrich U.; Botta M.; Maga G.
NON PEPTIDIC 14-3-3 INHIBITORS AND THE USE THEREOF
2011 BOTTA MAURIZIO; CORRADI VALENTINA; FALCHI FEDERICO; MANCINI EMANUELA; SANTUCCI MARIA ALESSANDRA
Fyn kinase in brain diseases and cancer: The search for inhibitors
2011 Schenone S.; Brullo C.; Musumeci F.; Biava M.; Falchi F.; Botta M.
N-[2-methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a Scaffold for the synthesis of inhibitors of Bcr-Abl
2011 Arioli F.; Borrelli S.; Colombo F.; Falchi F.; Filippi I.; Crespan E.; Naldini A.; Scalia G.; Silvani A.; Maga G.; Carraro F.; Botta M.; Passarella D.
Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation
2011 Maga G.; Falchi F.; Radi M.; Botta L.; Casaluce G.; Bernardini M.; Irannejad H.; Manetti F.; Garbelli A.; Samuele A.; Zanoli S.; Este J.A.; Gonzalez E.; Zucca E.; Paolucci S.; Baldanti F.; DeRijck J.; Debyser Z.; Botta M.
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case
2011 Corradi V; Mancini M; Santucci MA; Carlomagno T; Sanfelice D; Mori M; Vignaroli G; Falchi F; Manetti F; Radi M; Botta M
Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach
2012 Giovanni Maga, Anna Garbelli, Marco Radi, Federico Falchi, Alberta Samuele, Stefania Paolucci, Fausto Baldanti, Fabrizio Manetti, Sandra Beermann, Ursula Dietrich, Maurizio Botta
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation
2012 Radi M.; Evensen L.; Dreassi E.; Zamperini C.; Caporicci M.; Falchi F.; Musumeci F.; Schenone S.; Lorens J.B.; Botta M.
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors
2012 Radi M.; Falchi F.; Garbelli A.; Samuele A.; Bernardo V.; Paolucci S.; Baldanti F.; Schenone S.; Manetti F.; Maga G.; Botta M.
Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti-HIV Agents
2013 Tintori C.; Laurenzana I.; LaRocca F.; Falchi F.; Carraro F.; Ruiz A.; Este J.A.; Kissova M.; Crespan E.; Maga G.; Biava M.; Brullo C.; Schenone S.; Botta M.
Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening
2013 R. Buonfiglio; M. Ferraro; F. Falchi; A. Cavalli; M. Masetti; M. Recanatini
Novel antiproliferative chimeric compounds with marked histone deacetylase inhibitory activity.
2014 Giacomini E;Nebbioso A;Ciotta A;Ianni C;Falchi F;Roberti M;Tolomeo M;Grimaudo S;Cristina AD;Pipitone RM;Altucci L;Recanatini M
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents. | Radi M; Crespan E; Botta G; Falchi F; Maga G; Manetti F; Corradi V; Mancini M; Santucci MA; Schen...one S; Botta M. | 2008-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Pharmacophore modeling and molecular docking led to the discovery of inhibitors of human immunodeficiency virus-1 replication targeting the human cellular aspartic acid-glutamic acid-alanine-aspartic acid box polypeptide 3 | Maga G.; Falchi F.; Garbelli A.; Belfiore A.; Witvrouw M.; Manetti F.; Botta M. | 2008-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds | Manetti F.; Falchi F.; Crespan E.; Schenone S.; Maga G.; Botta M. | 2008-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data | Dreassi E.; Zizzari A.T.; Falchi F.; Schenone S.; Santucci A.; Maga G.; Botta M. | 2009-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| 3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors | Falchi F.; Manetti F.; Carraro F.; Naldini A.; Maga G.; Crespan E.; Schenone S.; Bruno O.; Brullo... C.; Botta M. | 2009-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase | Giovanni Maga, Federico Falchi, Anna Garbelli, Marco Radi, Stefania Paolucci, Fausto Baldanti, Ma...urizio Botta | 2010-01-01 | RETROVIROLOGY | - | 1.01 Articolo in rivista | - |
| Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: From docking false positives to ATP-noncompetitive inhibitors | Radi M.; Crespan E.; Falchi F.; Bernardo V.; Zanoli S.; Manetti F.; Schenone S.; Maga G.; Botta M. | 2010-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF | RADI MARCO; BOTTA MAURIZIO; FALCHI FEDERICO; MAGA GIOVANNI; BALDANTI FAUSTO; PAOLUCCI STEFANIA | 2011-01-01 | - | - | 6.01 Brevetto | - |
| Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication | Garbelli A.; Radi M.; Falchi F.; Beermann S.; Zanoli S.; Manetti F.; Dietrich U.; Botta M.; Maga G. | 2011-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| NON PEPTIDIC 14-3-3 INHIBITORS AND THE USE THEREOF | BOTTA MAURIZIO; CORRADI VALENTINA; FALCHI FEDERICO; MANCINI EMANUELA; SANTUCCI MARIA ALESSANDRA | 2011-01-01 | - | - | 6.01 Brevetto | - |
| Fyn kinase in brain diseases and cancer: The search for inhibitors | Schenone S.; Brullo C.; Musumeci F.; Biava M.; Falchi F.; Botta M. | 2011-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| N-[2-methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a Scaffold for the synthesis of inhibitors of Bcr-Abl | Arioli F.; Borrelli S.; Colombo F.; Falchi F.; Filippi I.; Crespan E.; Naldini A.; Scalia G.; Sil...vani A.; Maga G.; Carraro F.; Botta M.; Passarella D. | 2011-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation | Maga G.; Falchi F.; Radi M.; Botta L.; Casaluce G.; Bernardini M.; Irannejad H.; Manetti F.; Garb...elli A.; Samuele A.; Zanoli S.; Este J.A.; Gonzalez E.; Zucca E.; Paolucci S.; Baldanti F.; DeRijck J.; Debyser Z.; Botta M. | 2011-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case | Corradi V; Mancini M; Santucci MA; Carlomagno T; Sanfelice D; Mori M; Vignaroli G; Falchi F; Mane...tti F; Radi M; Botta M | 2011-01-01 | BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach | Giovanni Maga, Anna Garbelli, Marco Radi, Federico Falchi, Alberta Samuele, Stefania Paolucci, Fa...usto Baldanti, Fabrizio Manetti, Sandra Beermann, Ursula Dietrich, Maurizio Botta | 2012-01-01 | RETROVIROLOGY | - | 1.01 Articolo in rivista | - |
| A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation | Radi M.; Evensen L.; Dreassi E.; Zamperini C.; Caporicci M.; Falchi F.; Musumeci F.; Schenone S.;... Lorens J.B.; Botta M. | 2012-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors | Radi M.; Falchi F.; Garbelli A.; Samuele A.; Bernardo V.; Paolucci S.; Baldanti F.; Schenone S.; ...Manetti F.; Maga G.; Botta M. | 2012-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti-HIV Agents | Tintori C.; Laurenzana I.; LaRocca F.; Falchi F.; Carraro F.; Ruiz A.; Este J.A.; Kissova M.; Cre...span E.; Maga G.; Biava M.; Brullo C.; Schenone S.; Botta M. | 2013-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening | R. Buonfiglio; M. Ferraro; F. Falchi; A. Cavalli; M. Masetti; M. Recanatini | 2013-01-01 | JOURNAL OF CHEMICAL INFORMATION AND MODELING | - | 1.01 Articolo in rivista | - |
| Novel antiproliferative chimeric compounds with marked histone deacetylase inhibitory activity. | Giacomini E;Nebbioso A;Ciotta A;Ianni C;Falchi F;Roberti M;Tolomeo M;Grimaudo S;Cristina AD;Pipit...one RM;Altucci L;Recanatini M | 2014-01-01 | ACS MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
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