Sfoglia per Autore
Circular Dichroism: a Study of Reversible Binding HSA Binding of Lipocrine.
2009 A. De Simone; M. Pistolozzi; M. Rosini; C. Melchiorre; C. Bertucci
Circular dichroism in drug discovery and development: an abridged review.
2010 Bertucci C; Pistolozzi M; De Simone A.
Surface plasmon resonance assay for BACE-1 inhibitors’ characterization.
2010 De Simone, A.; Real, F.; Mancini, F.; Rovero, P.; Andrisano, V.; Bertucci, C.
Micro-immobilized enzyme reactor based on human recombinant beta secretase (hrBACE-1-microIMER) for liquid chromatography fast screening of inhibitors.
2010 De Simone, A.; Mancini, F.; Andrisano, V.
Structural characterization of p53 isoforms due to the polymorphism at codon 72 by Mass Spectrometry and Circular Dichroism.
2010 Naldi M.; Pistolozzi M.; Bertucci C.; De Simone A.; Altilia S.; Pierini M.; Franceschi C.; Salvioli S.; Andrisano V.
A multi-approach study for BACE-1 inhibitors characterization.
2010 Angela De Simone; F. Mancini; C. Bertucci; V. Andrisano
An Advanced Multiple Receptor Conformations Virtual Ligand Screening Protocol for the Identification of Novel BACE-1 Inhibitors
2011 Kacker, Puneet; Masetti, Matteo; De Simone, Angela; Bottegoni, Giovanni; Cavalli, Andrea
Reversible human serum albumin binding of lipocrine: a circular dichroism study.
2011 C. Bertucci; A. De Simone; M. Pistolozzi; M. Rosini
Beta-secretase as a target for Alzheimer's disease drug discovery: an overview of in vitro methods for characterization of inhibitors.
2011 F. Mancini; A. De Simone; V. Andrisano
Structural characterization of recombinant therapeutic proteins by circular dichroism.
2011 Bertucci C; Pistolozzi M; De Simone A.
Optical Biosensors and Applications to Drug Discovery and Development in Cancer Research
2012 Bertucci, Carlo; De Simone, Angela
Curcumin derivatives as beta-secretase (BACE1) inhibitors.
2012 De Simone, A; Mancini, F; Belluti, F; Bartolini, M; Bottegoni, G.; Rampa, A.; Cavalli, A.; Andrisano, V.
Identification of Novel BACE-1 Inhibitors through an Advanced Structure-Based Virtual Screening Protocol.
2012 Kacker, Puneet; De Simone, Angela; Masetti, Matteo; Bottegoni, Giovanni; Andrisano, Vincenza; Cavalli, Andrea
An immobilized enzyme reactor based on human recombinant betasecretase (hrBACE-1-IMER) for the fast processing of substrates and screening of inhibitors
2012 Chlebek, Jakub; De Simone, Angela; Mancini, Francesca; Andrisano, Vincenza
Amyloid beta-Peptide 25-35 Self Assembly and Its Inhibition: A Model Undecapeptide System to Gain Atomistic and Secondary Structure Details of the Alzheimer's Disease Process and Treatment
2012 Naldi M.; Fiori J.; Pistolozzi M.; Drake A.F.; Bertucci C.; Wu R.; Mlynarczyk K.; Filipek S.; De Simone A.; Andrisano V.
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation
2012 G. P. Chiriano; A. De Simone; F. Mancini; D. I. Perez; A. Cavalli; M. L. Bolognesi; G. Legname; A. Martinez; V. Andrisano; P. Carloni; M. Roberti
Protein Flexibility in Virtual Screening: The BACE-1 Case Study
2012 Cosconati S.; Marinelli L.; Di Leva F.S.; La Pietra V.; De Simone A.; Mancini F.; Andrisano V.; Novellino E.; Goodsell D.S.; Olson A.J.
Monitoring GSM peptide phosphorylation by Glycogen Synthase Kinase-3β using Electrospray Ionization Ion Trap Mass Spectrometry (ESI-IT-MS).
2013 D’Urzo A.; Fiori J.; De Simone A.; Andrisano V.
Synthesis, molecular modelling, in vitro biological profiling, and in vivo efficacy studies of a novel family of huprine-based multi-target anti-alzheimer compounds.
2013 Viayna, E.; Sola, I.; Bartolini, M.; De Simone, A.; Tapia-Rojas, C.; Carvajal, F. J.; Serrano, F. G.; Sabate, R.; Juárez, J.; Pérez, B.; Badia, A.; Luque, F. J.; Andrisano, V.; Clos, M. V.; Inestrosa, N. C.; Muñoz-Torrero, D. .
Optimization of natural compounds on-line screening by immobilized enzyme reactor based on human recombinant betasecretase (hrBACE-1-IMER).
2013 De Simone, A.; Seidl, C.; Santos, C.; Andrisano, V.
Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
---|---|---|---|---|---|---|
Circular Dichroism: a Study of Reversible Binding HSA Binding of Lipocrine. | A. De Simone; M. Pistolozzi; M. Rosini; C. Melchiorre; C. Bertucci | 2009-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
Circular dichroism in drug discovery and development: an abridged review. | Bertucci C; Pistolozzi M; De Simone A. | 2010-01-01 | ANALYTICAL AND BIOANALYTICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Surface plasmon resonance assay for BACE-1 inhibitors’ characterization. | De Simone, A.; Real, F.; Mancini, F.; Rovero, P.; Andrisano, V.; Bertucci, C. | 2010-01-01 | - | - | 4.03 Poster | - |
Micro-immobilized enzyme reactor based on human recombinant beta secretase (hrBACE-1-microIMER) for liquid chromatography fast screening of inhibitors. | De Simone, A.; Mancini, F.; Andrisano, V. | 2010-01-01 | - | - | 4.03 Poster | - |
Structural characterization of p53 isoforms due to the polymorphism at codon 72 by Mass Spectrometry and Circular Dichroism. | Naldi M.; Pistolozzi M.; Bertucci C.; De Simone A.; Altilia S.; Pierini M.; Franceschi C.; Salvio...li S.; Andrisano V. | 2010-01-01 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | - | 1.01 Articolo in rivista | - |
A multi-approach study for BACE-1 inhibitors characterization. | Angela De Simone; F. Mancini; C. Bertucci; V. Andrisano | 2010-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
An Advanced Multiple Receptor Conformations Virtual Ligand Screening Protocol for the Identification of Novel BACE-1 Inhibitors | Kacker, Puneet; Masetti, Matteo; De Simone, Angela; Bottegoni, Giovanni; Cavalli, Andrea | 2011-01-01 | - | - | 4.03 Poster | - |
Reversible human serum albumin binding of lipocrine: a circular dichroism study. | C. Bertucci; A. De Simone; M. Pistolozzi; M. Rosini | 2011-01-01 | CHIRALITY | - | 1.01 Articolo in rivista | - |
Beta-secretase as a target for Alzheimer's disease drug discovery: an overview of in vitro methods for characterization of inhibitors. | F. Mancini; A. De Simone; V. Andrisano | 2011-01-01 | ANALYTICAL AND BIOANALYTICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Structural characterization of recombinant therapeutic proteins by circular dichroism. | Bertucci C; Pistolozzi M; De Simone A. | 2011-01-01 | CURRENT PHARMACEUTICAL BIOTECHNOLOGY | - | 1.01 Articolo in rivista | - |
Optical Biosensors and Applications to Drug Discovery and Development in Cancer Research | Bertucci, Carlo; De Simone, Angela | 2012-01-01 | - | Vinood B. Patel | 2.01 Capitolo / saggio in libro | - |
Curcumin derivatives as beta-secretase (BACE1) inhibitors. | De Simone, A; Mancini, F; Belluti, F; Bartolini, M; Bottegoni, G.; Rampa, A.; Cavalli, A.; Andris...ano, V. | 2012-01-01 | - | - | 4.03 Poster | - |
Identification of Novel BACE-1 Inhibitors through an Advanced Structure-Based Virtual Screening Protocol. | Kacker, Puneet; De Simone, Angela; Masetti, Matteo; Bottegoni, Giovanni; Andrisano, Vincenza; Cav...alli, Andrea | 2012-01-01 | - | - | 4.03 Poster | - |
An immobilized enzyme reactor based on human recombinant betasecretase (hrBACE-1-IMER) for the fast processing of substrates and screening of inhibitors | Chlebek, Jakub; De Simone, Angela; Mancini, Francesca; Andrisano, Vincenza | 2012-01-01 | - | - | 4.03 Poster | - |
Amyloid beta-Peptide 25-35 Self Assembly and Its Inhibition: A Model Undecapeptide System to Gain Atomistic and Secondary Structure Details of the Alzheimer's Disease Process and Treatment | Naldi M.; Fiori J.; Pistolozzi M.; Drake A.F.; Bertucci C.; Wu R.; Mlynarczyk K.; Filipek S.; De ...Simone A.; Andrisano V. | 2012-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | - |
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation | G. P. Chiriano; A. De Simone; F. Mancini; D. I. Perez; A. Cavalli; M. L. Bolognesi; G. Legname; A.... Martinez; V. Andrisano; P. Carloni; M. Roberti | 2012-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Protein Flexibility in Virtual Screening: The BACE-1 Case Study | Cosconati S.; Marinelli L.; Di Leva F.S.; La Pietra V.; De Simone A.; Mancini F.; Andrisano V.; N...ovellino E.; Goodsell D.S.; Olson A.J. | 2012-01-01 | JOURNAL OF CHEMICAL INFORMATION AND MODELING | - | 1.01 Articolo in rivista | - |
Monitoring GSM peptide phosphorylation by Glycogen Synthase Kinase-3β using Electrospray Ionization Ion Trap Mass Spectrometry (ESI-IT-MS). | D’Urzo A.; Fiori J.; De Simone A.; Andrisano V. | 2013-01-01 | - | - | 4.03 Poster | - |
Synthesis, molecular modelling, in vitro biological profiling, and in vivo efficacy studies of a novel family of huprine-based multi-target anti-alzheimer compounds. | Viayna, E.; Sola, I.; Bartolini, M.; De Simone, A.; Tapia-Rojas, C.; Carvajal, F. J.; Serrano, F.... G.; Sabate, R.; Juárez, J.; Pérez, B.; Badia, A.; Luque, F. J.; Andrisano, V.; Clos, M. V.; Inestrosa, N. C.; Muñoz-Torrero, D. . | 2013-01-01 | - | - | 4.03 Poster | - |
Optimization of natural compounds on-line screening by immobilized enzyme reactor based on human recombinant betasecretase (hrBACE-1-IMER). | De Simone, A.; Seidl, C.; Santos, C.; Andrisano, V. | 2013-01-01 | - | - | 4.03 Poster | - |
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