Sfoglia per Autore
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
2011 Trazzi S.; Mitrugno V.M.; Valli E.; Fuchs C.; Rizzi S.; Guidi S.; Perini G.; Bartesaghi R.; Ciani E.
Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression
2012 Fuchs C; Ciani E; Guidi S; Trazzi S; Bartesaghi R
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells
2012 VALLI E; TRAZZI S; FUCHS C; ERRIQUEZ D; BARTESAGHI R; PERINI G; CIANI E
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for down syndrome.
2013 Trazzi S; Fuchs C; Valli E; Perini G; Bartesaghi R; Ciani E.
Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling.
2014 Fuchs C;Trazzi S;Torricella R;Viggiano R;De Franceschi M;Amendola E;Gross C;Calzà L;Bartesaghi R;Ciani E
APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome.
2014 Trazzi S;Fuchs C;De Franceschi M;Mitrugno VM;Bartesaghi R;Ciani E
Mapping pathological phenotypes in a mouse model of CDKL5 disorder.
2014 Amendola E;Zhan Y;Mattucci C;Castroflorio E;Calcagno E;Fuchs C;Lonetti G;Silingardi D;Vyssotski AL;Farley D;Ciani E;Pizzorusso T;Giustetto M;Gross CT
Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder
2015 Fuchs, C.; Rimondini, R.; Viggiano, R.; Trazzi, S.; De Franceschi, M.; Bartesaghi, R.; Ciani, E.
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder
2016 Trazzi, Stefania; Fuchs, Claudia; Viggiano, Rocchina; De Franceschi, Marianna; Valli, Emanuele; Jedynak, Paulina; Hansen, Finn K; Perini, Giovanni; Rimondini, Roberto; Kurz, Thomas; Bartesaghi, Renata; Ciani, Elisabetta
CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder
2018 Trazzi, Stefania; De Franceschi, Marianna; Fuchs, Claudia; Bastianini, Stefano; Viggiano, Rocchina; Lupori, Leonardo; Mazziotti, Raffaele; Medici, Giorgio; Martire, Viviana Lo; Ren, Elisa; Rimondini, Roberto; Zoccoli, Giovanna; Bartesaghi, Renata; Pizzorusso, Tommaso; Ciani, Elisabetta*
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder
2018 Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Lo Martire, Viviana; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder
2018 Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Martire, Viviana Lo; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta*
Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice
2018 Fuchs, Claudia; Fustini, Norma; Trazzi, Stefania; Gennaccaro, Laura; Rimondini, Roberto; Ciani, Elisabetta*
Site-specific abnormalities in the visual system of a mouse model of CDKL5 deficiency disorder
2019 Lupori L.; Sagona G.; Fuchs C.; Mazziotti R.; Stefanov A.; Putignano E.; Napoli D.; Strettoi E.; Ciani E.; Pizzorusso T.
Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist
2019 Ren E.; Roncace V.; Trazzi S.; Fuchs C.; Medici G.; Gennaccaro L.; Loi M.; Galvani G.; Ye K.; Rimondini R.; Aicardi G.; Ciani E.
CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019)
2019 Fuchs C.; Medici G.; Trazzi S.; Gennaccaro L.; Galvani G.; Berteotti C.; Ren E.; Loi M.; Ciani E.
Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist
2020 Anna Cecilia Berardi, Claudia Fuchs, Laura Gennaccaro, Vincenzo Roncacè, Yassine Aitbali, Elisa Ren, Stefania Trazzi, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani
Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons
2020 Loi M.; Trazzi S.; Fuchs C.; Galvani G.; Medici G.; Gennaccaro L.; Tassinari M.; Ciani E.
Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder
2020 Fuchs C.; Gennaccaro L.; Ren E.; Galvani G.; Trazzi S.; Medici G.; Loi M.; Conway E.; Devinsky O.; Rimondini R.; Ciani E.
The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo
2020 Trovo L.; Fuchs C.; De Rosa R.; Barbiero I.; Tramarin M.; Ciani E.; Rusconi L.; Kilstrup-Nielsen C.
Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
---|---|---|---|---|---|---|
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome. | Trazzi S.; Mitrugno V.M.; Valli E.; Fuchs C.; Rizzi S.; Guidi S.; Perini G.; Bartesaghi R.; Ciani E. | 2011-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression | Fuchs C; Ciani E; Guidi S; Trazzi S; Bartesaghi R | 2012-01-01 | LABORATORY INVESTIGATION | - | 1.01 Articolo in rivista | - |
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells | VALLI E; TRAZZI S; FUCHS C; ERRIQUEZ D; BARTESAGHI R; PERINI G; CIANI E | 2012-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS | - | 1.01 Articolo in rivista | - |
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for down syndrome. | Trazzi S; Fuchs C; Valli E; Perini G; Bartesaghi R; Ciani E. | 2013-01-01 | THE JOURNAL OF BIOLOGICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling. | Fuchs C;Trazzi S;Torricella R;Viggiano R;De Franceschi M;Amendola E;Gross C;Calzà L;Bartesaghi R;...Ciani E | 2014-01-01 | NEUROBIOLOGY OF DISEASE | - | 1.01 Articolo in rivista | - |
APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome. | Trazzi S;Fuchs C;De Franceschi M;Mitrugno VM;Bartesaghi R;Ciani E | 2014-01-01 | NEUROBIOLOGY OF DISEASE | - | 1.01 Articolo in rivista | - |
Mapping pathological phenotypes in a mouse model of CDKL5 disorder. | Amendola E;Zhan Y;Mattucci C;Castroflorio E;Calcagno E;Fuchs C;Lonetti G;Silingardi D;Vyssotski A...L;Farley D;Ciani E;Pizzorusso T;Giustetto M;Gross CT | 2014-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | 10.1371_journal.pone.0091613.PDF |
Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder | Fuchs, C.; Rimondini, R.; Viggiano, R.; Trazzi, S.; De Franceschi, M.; Bartesaghi, R.; Ciani, E. | 2015-01-01 | NEUROBIOLOGY OF DISEASE | - | 1.01 Articolo in rivista | - |
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder | Trazzi, Stefania; Fuchs, Claudia; Viggiano, Rocchina; De Franceschi, Marianna; Valli, Emanuele; J...edynak, Paulina; Hansen, Finn K; Perini, Giovanni; Rimondini, Roberto; Kurz, Thomas; Bartesaghi, Renata; Ciani, Elisabetta | 2016-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder | Trazzi, Stefania; De Franceschi, Marianna; Fuchs, Claudia; Bastianini, Stefano; Viggiano, Rocchin...a; Lupori, Leonardo; Mazziotti, Raffaele; Medici, Giorgio; Martire, Viviana Lo; Ren, Elisa; Rimondini, Roberto; Zoccoli, Giovanna; Bartesaghi, Renata; Pizzorusso, Tommaso; Ciani, Elisabetta* | 2018-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | trazzi2018 .pdf |
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder | Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Lo Mar...tire, Viviana; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta | 2018-01-01 | NEURAL PLASTICITY | - | 1.01 Articolo in rivista | - |
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder | Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Martir...e, Viviana Lo; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta* | 2018-01-01 | NEURAL PLASTICITY | - | 1.01 Articolo in rivista | 9726950(1).pdf; Supplementary Materials.zip |
Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice | Fuchs, Claudia; Fustini, Norma; Trazzi, Stefania; Gennaccaro, Laura; Rimondini, Roberto; Ciani, E...lisabetta* | 2018-01-01 | EUROPEAN JOURNAL OF NEUROSCIENCE | - | 1.01 Articolo in rivista | - |
Site-specific abnormalities in the visual system of a mouse model of CDKL5 deficiency disorder | Lupori L.; Sagona G.; Fuchs C.; Mazziotti R.; Stefanov A.; Putignano E.; Napoli D.; Strettoi E.; ...Ciani E.; Pizzorusso T. | 2019-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | ddz102.pdf; supplementary_material_ddz102.pdf |
Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist | Ren E.; Roncace V.; Trazzi S.; Fuchs C.; Medici G.; Gennaccaro L.; Loi M.; Galvani G.; Ye K.; Rim...ondini R.; Aicardi G.; Ciani E. | 2019-01-01 | FRONTIERS IN CELLULAR NEUROSCIENCE | - | 1.01 Articolo in rivista | fncel-13-00169.pdf |
CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019) | Fuchs C.; Medici G.; Trazzi S.; Gennaccaro L.; Galvani G.; Berteotti C.; Ren E.; Loi M.; Ciani E. | 2019-01-01 | BRAIN PATHOLOGY | - | 1.01 Articolo in rivista | - |
Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist |
Anna Cecilia Berardi, Claudia Fuchs, Laura Gennaccaro, Vincenzo Roncacè, Yassine Aitbali, Elisa ...Ren, Stefania Trazzi, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani |
2020-01-01 | - | - | 4.03 Poster | - |
Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons | Loi M.; Trazzi S.; Fuchs C.; Galvani G.; Medici G.; Gennaccaro L.; Tassinari M.; Ciani E. | 2020-01-01 | MOLECULAR NEUROBIOLOGY | - | 1.01 Articolo in rivista | - |
Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder | Fuchs C.; Gennaccaro L.; Ren E.; Galvani G.; Trazzi S.; Medici G.; Loi M.; Conway E.; Devinsky O....; Rimondini R.; Ciani E. | 2020-01-01 | NEUROPHARMACOLOGY | - | 1.01 Articolo in rivista | - |
The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo | Trovo L.; Fuchs C.; De Rosa R.; Barbiero I.; Tramarin M.; Ciani E.; Rusconi L.; Kilstrup-Nielsen C. | 2020-01-01 | NEUROBIOLOGY OF DISEASE | - | 1.01 Articolo in rivista | 1-s2.0-S0969996120300668-main.pdf |
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