Sfoglia per Autore
Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells
2010 Porro A.; Haber M.; Diolaiti D.; Iraci N.; Henderson M.; Gherardi S.; Valli E.; Munoz M.A.; Xue C.; Flemming C.; Schwab M.; Wong J.H.; Marshall G.M.; Della Valle G.; Norris M.D.; Perini G.
A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF
2011 Iraci N.; Diolaiti D.; Papa A.; Porro A.; Valli E.; Gherardi S.; Herold S.; Eilers M.; Bernardoni R.; Della Valle G.; Perini G.
SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability.
2011 G.M. Marshall; P.Y. Liu; S. Gherardi; C.J. Scarlett; A. Bedalov; N. Xu; N. Iraci; E. Valli; D. Ling; W. Thomas; M. van Bekkum; E. Sekyere; K. Jankowski; T. Trahair; K.L. Mackenzie; M. Haber; M.D. Norris; A.V. Biankin; G. Perini; T. Liu.
c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in Chronic Myelogenous Leukemia CD34+ hematopoietic progenitor cells
2011 A. Porro; N. Iraci; S. Soverini; D. Diolaiti; S. Gherardi; C. Terragna; S. Durante; E. Valli; T. Kalebic; R. Bernardoni; C. Perrod; M. Haber; M.D. Norris; M. Baccarani; G. Martinelli; G. Perini
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
2011 Trazzi S.; Mitrugno V.M.; Valli E.; Fuchs C.; Rizzi S.; Guidi S.; Perini G.; Bartesaghi R.; Ciani E.
A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma
2012 Giovanni Perini; Emanuele Valli; Samuele Gherardi; Simone Di Giacomo; Giorgio Milazzo; Timothy R. Wagenaar; Michael R. Green
The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy
2012 Neri M; Valli E; Alfano G; Bovolenta M; Spitali P; Rapezzi C; Muntoni F; Banfi S; Perini G; Gualandi F; Ferlini A.
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells
2012 VALLI E; TRAZZI S; FUCHS C; ERRIQUEZ D; BARTESAGHI R; PERINI G; CIANI E
IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia.
2012 Iacobucci I.; Iraci N.; Messina M.; Lonetti A.; Chiaretti S.; Valli E.; Ferrari A.; Papayannidis C.; Paoloni F.; Vitale A.; Storlazzi C.T.; Ottaviani E.; Guadagnuolo V.; Durante S.; Vignetti M.; Soverini S.; Pane F.; Foà R.; Baccarani M.; Müschen M.; Perini G.; Martinelli G.
The DMD Locus Harbours Multiple Long Non-Coding RNAs Which Orchestrate and Control Transcription of Muscle Dystrophin mRNA Isoforms.
2012 Bovolenta M.; Erriquez D.; Valli E.; Brioschi S.; Scotton C.; Neri M.; Falzarano M.S.; Gherardi S.; Fabris M.; Rimessi P.; Gualandi F.; Perini G.; Ferlini A.
N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma
2012 Fletcher J.I.; Gherardi S.; Murray J.; Burkhart C.A.; Russell A.; Valli E.; Smith J.; Oberthuer A.; Ashton L.J.; London W.B.; Marshall G.M.; Norris M.D.; Perini G.; Haber M.
MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin.
2013 Gherardi S; Valli E; Erriquez D; Perini G.
Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications.
2013 Corvetta D; Chayka O; Gherardi S; D'Acunto CW; Cantilena S; Valli E; Piotrowska I; Perini G; Sala A.
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for down syndrome.
2013 Trazzi S; Fuchs C; Valli E; Perini G; Bartesaghi R; Ciani E.
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder
2016 Trazzi, Stefania; Fuchs, Claudia; Viggiano, Rocchina; De Franceschi, Marianna; Valli, Emanuele; Jedynak, Paulina; Hansen, Finn K; Perini, Giovanni; Rimondini, Roberto; Kurz, Thomas; Bartesaghi, Renata; Ciani, Elisabetta
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma
2019 Laura D. Gamble, Stefania Purgato, Jayne Murray, Lin Xiao, Denise M. T. Yu, Kimberley M. Hanssen, Federico M. Giorgi, Daniel R. Carter, Andrew J. Gifford, Emanuele Valli, Giorgio Milazzo, Alvin Kamili, Chelsea Mayoh, Bing Liu, Georgina Eden, Sara Sarraf, Sophie Allan, Simone Di Giacomo, Claudia L. Flemming, Amanda J. Russell, Belamy B. Cheung, Andre Oberthuer, Wendy B. London, Matthias Fischer, Toby N. Trahair, Jamie I. Fletcher, Glenn M. Marshall, David S. Ziegler, Michael D. Hogarty, Mark R. Burns, Giovanni Perini, Murray D. Norris, and Michelle Haber
A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma
2021 Gamble L.D.; Purgato S.; Henderson M.J.; Di Giacomo S.; Russell A.J.; Pigini P.; Murray J.; Valli E.; Milazzo G.; Giorgi F.M.; Cowley M.; Ashton L.J.; Bhalshankar J.; Schleiermacher G.; Rihani A.; Van Maerken T.; Vandesompele J.; Speleman F.; Versteeg R.; Koster J.; Eggert A.; Noguera R.; Stallings R.L.; Tonini G.P.; Fong K.; Vaksman Z.; Diskin S.J.; Maris J.M.; London W.B.; Marshall G.M.; Ziegler D.S.; Hogarty M.D.; Perini G.; Norris M.D.; Haber M.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells | Porro A.; Haber M.; Diolaiti D.; Iraci N.; Henderson M.; Gherardi S.; Valli E.; Munoz M.A.; Xue C....; Flemming C.; Schwab M.; Wong J.H.; Marshall G.M.; Della Valle G.; Norris M.D.; Perini G. | 2010-01-01 | THE JOURNAL OF BIOLOGICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF | Iraci N.; Diolaiti D.; Papa A.; Porro A.; Valli E.; Gherardi S.; Herold S.; Eilers M.; Bernardoni... R.; Della Valle G.; Perini G. | 2011-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability. | G.M. Marshall; P.Y. Liu; S. Gherardi; C.J. Scarlett; A. Bedalov; N. Xu; N. Iraci; E. Valli; D. Li...ng; W. Thomas; M. van Bekkum; E. Sekyere; K. Jankowski; T. Trahair; K.L. Mackenzie; M. Haber; M.D. Norris; A.V. Biankin; G. Perini; T. Liu. | 2011-01-01 | PLOS GENETICS | - | 1.01 Articolo in rivista | - |
| c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in Chronic Myelogenous Leukemia CD34+ hematopoietic progenitor cells | A. Porro; N. Iraci; S. Soverini; D. Diolaiti; S. Gherardi; C. Terragna; S. Durante; E. Valli; T. ...Kalebic; R. Bernardoni; C. Perrod; M. Haber; M.D. Norris; M. Baccarani; G. Martinelli; G. Perini | 2011-01-01 | MOLECULAR CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome. | Trazzi S.; Mitrugno V.M.; Valli E.; Fuchs C.; Rizzi S.; Guidi S.; Perini G.; Bartesaghi R.; Ciani E. | 2011-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma | Giovanni Perini; Emanuele Valli; Samuele Gherardi; Simone Di Giacomo; Giorgio Milazzo; Timothy R.... Wagenaar; Michael R. Green | 2012-01-01 | - | - | 4.03 Poster | - |
| The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy | Neri M; Valli E; Alfano G; Bovolenta M; Spitali P; Rapezzi C; Muntoni F; Banfi S; Perini G; Guala...ndi F; Ferlini A. | 2012-01-01 | BMC MEDICAL GENETICS | - | 1.01 Articolo in rivista | 1471-2350-13-20.pdf |
| CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells | VALLI E; TRAZZI S; FUCHS C; ERRIQUEZ D; BARTESAGHI R; PERINI G; CIANI E | 2012-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS | - | 1.01 Articolo in rivista | - |
| IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia. | Iacobucci I.; Iraci N.; Messina M.; Lonetti A.; Chiaretti S.; Valli E.; Ferrari A.; Papayannidis ...C.; Paoloni F.; Vitale A.; Storlazzi C.T.; Ottaviani E.; Guadagnuolo V.; Durante S.; Vignetti M.; Soverini S.; Pane F.; Foà R.; Baccarani M.; Müschen M.; Perini G.; Martinelli G. | 2012-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | journal.pone.0040934.PDF |
| The DMD Locus Harbours Multiple Long Non-Coding RNAs Which Orchestrate and Control Transcription of Muscle Dystrophin mRNA Isoforms. | Bovolenta M.; Erriquez D.; Valli E.; Brioschi S.; Scotton C.; Neri M.; Falzarano M.S.; Gherardi S....; Fabris M.; Rimessi P.; Gualandi F.; Perini G.; Ferlini A. | 2012-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | - |
| N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma | Fletcher J.I.; Gherardi S.; Murray J.; Burkhart C.A.; Russell A.; Valli E.; Smith J.; Oberthuer A....; Ashton L.J.; London W.B.; Marshall G.M.; Norris M.D.; Perini G.; Haber M. | 2012-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin. | Gherardi S; Valli E; Erriquez D; Perini G. | 2013-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications. | Corvetta D; Chayka O; Gherardi S; D'Acunto CW; Cantilena S; Valli E; Piotrowska I; Perini G; Sala A. | 2013-01-01 | THE JOURNAL OF BIOLOGICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for down syndrome. | Trazzi S; Fuchs C; Valli E; Perini G; Bartesaghi R; Ciani E. | 2013-01-01 | THE JOURNAL OF BIOLOGICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder | Trazzi, Stefania; Fuchs, Claudia; Viggiano, Rocchina; De Franceschi, Marianna; Valli, Emanuele; J...edynak, Paulina; Hansen, Finn K; Perini, Giovanni; Rimondini, Roberto; Kurz, Thomas; Bartesaghi, Renata; Ciani, Elisabetta | 2016-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma | Laura D. Gamble, Stefania Purgato, Jayne Murray, Lin Xiao, Denise M. T. Yu, Kimberley M. Hanssen,... Federico M. Giorgi, Daniel R. Carter, Andrew J. Gifford, Emanuele Valli, Giorgio Milazzo, Alvin Kamili, Chelsea Mayoh, Bing Liu, Georgina Eden, Sara Sarraf, Sophie Allan, Simone Di Giacomo, Claudia L. Flemming, Amanda J. Russell, Belamy B. Cheung, Andre Oberthuer, Wendy B. London, Matthias Fischer, Toby N. Trahair, Jamie I. Fletcher, Glenn M. Marshall, David S. Ziegler, Michael D. Hogarty, Mark R. Burns, Giovanni Perini, Murray D. Norris, and Michelle Haber | 2019-01-01 | SCIENCE TRANSLATIONAL MEDICINE | - | 1.01 Articolo in rivista | - |
| A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma | Gamble L.D.; Purgato S.; Henderson M.J.; Di Giacomo S.; Russell A.J.; Pigini P.; Murray J.; Valli... E.; Milazzo G.; Giorgi F.M.; Cowley M.; Ashton L.J.; Bhalshankar J.; Schleiermacher G.; Rihani A.; Van Maerken T.; Vandesompele J.; Speleman F.; Versteeg R.; Koster J.; Eggert A.; Noguera R.; Stallings R.L.; Tonini G.P.; Fong K.; Vaksman Z.; Diskin S.J.; Maris J.M.; London W.B.; Marshall G.M.; Ziegler D.S.; Hogarty M.D.; Perini G.; Norris M.D.; Haber M. | 2021-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-13-01807-v2.pdf |
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