Sfoglia per Autore
Multitarget-directed drug design strategy: novel hybrid compounds between lipocrine and carvedilol
2007 Rosini M; Simoni E; Bolognesi ML; Andrisano V; Bartolini M; Tarozzi a; Hrelia P; Mellor I; Melchiorre C.
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush
2008 M. Rosini; E. Simoni; M. Bartolini; A. Cavalli; L. Ceccarini; N. Pascu; D. W. McClymont; A. Tarozzi; M. L. Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease
2009 M. Rosini; M. Bartolini; E. Simoni; C. Gotti; D. McClymont; ML Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre
Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent
2010 A. Milelli; A. Minarini; C. Melchiorre; M. Micco; E. Simoni; G. Zuccari; L. Raffaghello; C. Stefanelli; M. Zini; V. Tumiatti
Curcumin analogs as multi-target antioxidants: focus on mitochondria.
2010 E. Simoni; M. Rosini; C. Bergamini; R. Fato; M.L. Bolognesi; A. Cavalli; R. Motterlini; G. Lenaz; C. Melchiorre
Mitochondria-directed antioxidants in Alzheimer's disease.
2010 M. Rosini; E. Simoni; M. L. Bolognesi; C. Bergamini; R. Fato; G. Lenaz; C. Melchiorre
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents.
2010 Simoni E.; Bergamini C.; Fato R.; Tarozzi A.; Bains S.; Motterlini R.; Cavalli A.; Bolognesi M.L.; Minarini A.; Hrelia P.; Lenaz G.; Rosini M.; Melchiorre C.
Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment
2011 A. Minarini; A. Milelli; V. Tumiatti; E. Simoni; M. L. Bolognesi; V. Andrisano; M. Bartolini; E. Motori; C. Angeloni ; S. Hrelia; C.Melchiorre
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease
2011 Bolognesi M.L.; Simoni E.; Rosini M.; Minarini A.; Tumiatti V.; Melchiorre C
Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease.
2011 M. Rosini; E. Simoni; M. Bartolini; A. Tarozzi; R. Matera; A. Milelli; P. Hrelia; V. Andrisano; M.L. Bolognesi; C. Melchiorre
Combining galantamine and memantine in dual-target new chemical entities for the treatment of Alzheimer’s disease
2012 Simoni E.; Daniele S.; Bottegoni G.; Pizzirani D.; Tarozzo G.; Reggiani A.; Trincavelli M.L.; Martini C.; Piomelli D.; Melchiorre C.; Rosini M.; Cavalli A.
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment.
2012 Minarini A.; Milelli A.; Tumiatti V.; Rosini M.; Simoni E.; Bolognesi M.L.; Andrisano V.; Bartolini M.; Motori E.; Angeloni C.; Hrelia S.
Rational design of dimebon bivalent ligands against Alzheimer’s disease
2012 Simoni E.; Rosini M.; Bartolini M.; Andrisano V.; Soriano E.; Marco-Contelles J.; Melchiorre C.; Bolognesi M.L.
Multifunctional Tacrine Derivatives in Alzheimer’s Disease
2013 Anna Minarini; Andrea Milelli; Elena Simoni; Michela Rosini; Maria Laura Bolognesi; Chiara Marchetti; Vincenzo Tumiatti
Quinones bearing non-steroidal anti-inflammatory fragments as multitarget ligands for Alzheimer’s disease
2013 Federica Prati;Manuela Bartolini;Elena Simoni;Angela De Simone;Antonella Pinto;Vincenza Andrisano;Maria Laura Bolognesi
The bivalent ligand approach as a tool for improving the in vitro anti-Alzheimer multitarget profile of dimebon
2013 Michela Rosini; Elena Simoni; Manuela Bartolini; Elena Soriano; José Marco-Contelles; Vincenza Andrisano; Barbara Monti; Manfred Windisch; Birgit Hutter-Paier; David W. McClymont; Ian R. Mellor; Maria Laura Bolognesi
Natural-product-inspired modulators of Alzheimer’s disease: focus on amyloid and oxidative stress
2014 Rosini, M.; Simoni, E.; Lanni, C.; Bartolini, M.; Pinto, A.; Fiori, J.; Andrisano, V.; Racchi, M.; Minarini, A.
Multi-target Design Strategies in the Context of Alzheimer's Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces
2014 Michela Rosini; Elena Simoni; Anna Minarini; Carlo Melchiorre
Exploring the effects of isothiocyanates on chemotherapeutic drugs
2014 Anna Minarini; Andrea Milelli; Carmela Fimognari; Elena Simoni; Eleonora Turrini; Vincenzo Tumiatti
Oxidative stress in Alzheimer’s disease: are we connecting the dots?
2014 Michela Rosini; Elena Simoni; Andrea Milelli; Anna Minarini; Carlo Melchiorre
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Multitarget-directed drug design strategy: novel hybrid compounds between lipocrine and carvedilol | Rosini M; Simoni E; Bolognesi ML; Andrisano V; Bartolini M; Tarozzi a; Hrelia P; Mellor I; Melchi...orre C. | 2007-01-01 | - | s.n | 4.01 Contributo in Atti di convegno | - |
| Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush | M. Rosini; E. Simoni; M. Bartolini; A. Cavalli; L. Ceccarini; N. Pascu; D. W. McClymont; A. Taroz...zi; M. L. Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre | 2008-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease | M. Rosini; M. Bartolini; E. Simoni; C. Gotti; D. McClymont; ML Bolognesi; A. Minarini; V. Tumiatt...i; V. Andrisano; I. R. Mellor; C. Melchiorre | 2009-01-01 | DRUGS OF THE FUTURE | - | 4.02 Riassunto (Abstract) | - |
| Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent | A. Milelli; A. Minarini; C. Melchiorre; M. Micco; E. Simoni; G. Zuccari; L. Raffaghello; C. Stefa...nelli; M. Zini; V. Tumiatti | 2010-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Curcumin analogs as multi-target antioxidants: focus on mitochondria. | E. Simoni; M. Rosini; C. Bergamini; R. Fato; M.L. Bolognesi; A. Cavalli; R. Motterlini; G. Lenaz;... C. Melchiorre | 2010-01-01 | - | s. n. | 4.02 Riassunto (Abstract) | - |
| Mitochondria-directed antioxidants in Alzheimer's disease. | M. Rosini; E. Simoni; M. L. Bolognesi; C. Bergamini; R. Fato; G. Lenaz; C. Melchiorre | 2010-01-01 | - | s. n. | 4.02 Riassunto (Abstract) | - |
| Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. | Simoni E.; Bergamini C.; Fato R.; Tarozzi A.; Bains S.; Motterlini R.; Cavalli A.; Bolognesi M.L....; Minarini A.; Hrelia P.; Lenaz G.; Rosini M.; Melchiorre C. | 2010-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment | A. Minarini; A. Milelli; V. Tumiatti; E. Simoni; M. L. Bolognesi; V. Andrisano; M. Bartolini; E. ...Motori; C. Angeloni ; S. Hrelia; C.Melchiorre | 2011-01-01 | - | 2011 Università del Salento – Coordinamento SIBA- | 4.02 Riassunto (Abstract) | - |
| Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease | Bolognesi M.L.; Simoni E.; Rosini M.; Minarini A.; Tumiatti V.; Melchiorre C | 2011-01-01 | CURRENT TOPICS IN MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease. | M. Rosini; E. Simoni; M. Bartolini; A. Tarozzi; R. Matera; A. Milelli; P. Hrelia; V. Andrisano; M....L. Bolognesi; C. Melchiorre | 2011-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Combining galantamine and memantine in dual-target new chemical entities for the treatment of Alzheimer’s disease | Simoni E.; Daniele S.; Bottegoni G.; Pizzirani D.; Tarozzo G.; Reggiani A.; Trincavelli M.L.; Mar...tini C.; Piomelli D.; Melchiorre C.; Rosini M.; Cavalli A. | 2012-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. | Minarini A.; Milelli A.; Tumiatti V.; Rosini M.; Simoni E.; Bolognesi M.L.; Andrisano V.; Bartoli...ni M.; Motori E.; Angeloni C.; Hrelia S. | 2012-01-01 | NEUROPHARMACOLOGY | - | 1.01 Articolo in rivista | - |
| Rational design of dimebon bivalent ligands against Alzheimer’s disease | Simoni E.; Rosini M.; Bartolini M.; Andrisano V.; Soriano E.; Marco-Contelles J.; Melchiorre C.; ...Bolognesi M.L. | 2012-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Multifunctional Tacrine Derivatives in Alzheimer’s Disease | Anna Minarini; Andrea Milelli; Elena Simoni; Michela Rosini; Maria Laura Bolognesi; Chiara Marche...tti; Vincenzo Tumiatti | 2013-01-01 | CURRENT TOPICS IN MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Quinones bearing non-steroidal anti-inflammatory fragments as multitarget ligands for Alzheimer’s disease | Federica Prati;Manuela Bartolini;Elena Simoni;Angela De Simone;Antonella Pinto;Vincenza Andrisano...;Maria Laura Bolognesi | 2013-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| The bivalent ligand approach as a tool for improving the in vitro anti-Alzheimer multitarget profile of dimebon | Michela Rosini; Elena Simoni; Manuela Bartolini; Elena Soriano; José Marco-Contelles; Vincenza An...drisano; Barbara Monti; Manfred Windisch; Birgit Hutter-Paier; David W. McClymont; Ian R. Mellor; Maria Laura Bolognesi | 2013-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Natural-product-inspired modulators of Alzheimer’s disease: focus on amyloid and oxidative stress | Rosini, M.; Simoni, E.; Lanni, C.; Bartolini, M.; Pinto, A.; Fiori, J.; Andrisano, V.; Racchi, M....; Minarini, A. | 2014-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Multi-target Design Strategies in the Context of Alzheimer's Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces | Michela Rosini; Elena Simoni; Anna Minarini; Carlo Melchiorre | 2014-01-01 | NEUROCHEMICAL RESEARCH | - | 1.01 Articolo in rivista | - |
| Exploring the effects of isothiocyanates on chemotherapeutic drugs |
Anna Minarini; Andrea Milelli; Carmela Fimognari; Elena Simoni; Eleonora Turrini; Vincenzo Tumiatti |
2014-01-01 | EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY | - | 1.01 Articolo in rivista | - |
| Oxidative stress in Alzheimer’s disease: are we connecting the dots? | Michela Rosini; Elena Simoni; Andrea Milelli; Anna Minarini; Carlo Melchiorre | 2014-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
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